27,28-dihydrodiolallitinib

Base Information

Chemical Name:27,28-dihydrodiolallitinib
CAS No.:1469980-18-4
Molecular Formula:C₂₄H₂₀ClFN₄O₄
Molecular Weight:482.899
Hs Code.:

Synonyms:27,28-dihydrodiolallitinib

Suppliers and Price of 27,28-dihydrodiolallitinib

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 27,28-dihydrodiolallitinib

Chemical Property:

Purity/Quality:

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Technology Process of 27,28-dihydrodiolallitinib

There total 3 articles about 27,28-dihydrodiolallitinib which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 897383-62-9
N-(4-(4-(3-fluorobenzyloxy)-3-chlorophenylamino)quinazolin-6-yl)acrylamide

: 77-92-9,906507-37-7
citric acid

: 1469980-18-4
27,28-dihydrodiolallitinib

Guidance literature:: With potassium osmate(VI); 4-methylmorpholine N-oxide; In water; acetone; at 20 ℃; for 48h;
DOI:10.1124/dmd.113.056341

Reference yield:

: 70-18-8
GLUTATHIONE

: 1636145-49-7
allitinib epoxide

: 845271-71-8
N⁴-[3-chloro-4-(3-fluoro-benzyloxy)-phenyl]-quinazoline-4,6-diamine

: C₃₃H₃₃ClFN₇O₉S

: 1469980-18-4
27,28-dihydrodiolallitinib

Guidance literature:: With ethylenediaminetetraacetic acid; magnesium chloride; In aq. phosphate buffer; dimethyl sulfoxide; at 37 ℃; for 1h; pH=7.4; Enzymatic reaction;
DOI:10.1124/dmd.113.056341

Reference yield:

: allitinib tosylate

: 1469980-18-4
27,28-dihydrodiolallitinib

Guidance literature:: Multi-step reaction with 2 steps

1: dihydrogen peroxide; formic acid / 3 h / 45 °C

2: magnesium chloride; ethylenediaminetetraacetic acid / dimethyl sulfoxide; aq. phosphate buffer / 1 h / 37 °C / pH 7.4 / Enzymatic reaction

With formic acid; ethylenediaminetetraacetic acid; dihydrogen peroxide; magnesium chloride; In aq. phosphate buffer; dimethyl sulfoxide;
DOI:10.1124/dmd.113.056341