4-Methylthiazole-2-carbonitrile

Base Information

Chemical Name:4-Methylthiazole-2-carbonitrile
CAS No.:100516-98-1
Molecular Formula:C5H4N2S
Molecular Weight:124.17
Hs Code.:2934100090
European Community (EC) Number:625-683-8
DSSTox Substance ID:DTXSID10584785
Wikidata:Q82476507
Mol file:100516-98-1.mol

Synonyms:4-Methylthiazole-2-carbonitrile;100516-98-1;4-METHYL-1,3-THIAZOLE-2-CARBONITRILE;4-METHYL-2-THIAZOLECARBONITRILE;2-Thiazolecarbonitrile, 4-methyl-;4-METHYLTHIAZOLE-2-CARBONITRILE 97;MFCD08276856;SCHEMBL128311;4-methyl-thiazole-2-carbonitrile;DTXSID10584785;ZLJOKRUAKFPDRN-UHFFFAOYSA-N;AKOS016009427;4-Methylthiazole-2-carbonitrile, 97%;CS-W011180;PB10548;AS-50562;SY045505;EN300-130050;P10584;A856559;J-000154;Z1255395879

Suppliers and Price of 4-Methylthiazole-2-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Methyl-2-thiazolecarbonitrile
500mg
$ 310.00

Sigma-Aldrich
4-Methylthiazole-2-carbonitrile 97%
1g
$ 176.00

Sigma-Aldrich
4-Methylthiazole-2-carbonitrile 97%
5g
$ 580.00

Matrix Scientific
4-Methyl-2-thiazolecarbonitrile 97%
5g
$ 2369.00

Matrix Scientific
4-Methyl-2-thiazolecarbonitrile 97%
1g
$ 822.00

Crysdot
4-Methylthiazole-2-carbonitrile 95+%
5g
$ 502.00

Chemenu
4-methyl-1,3-thiazole-2-carbonitrile 97%
10g
$ 825.00

Chemenu
4-methyl-1,3-thiazole-2-carbonitrile 97%
5g
$ 495.00

Apolloscientific
4-Methylthiazole-2-carbonitrile 95%
1g
$ 370.00

Apolloscientific
4-Methylthiazole-2-carbonitrile 95%
250mg
$ 175.00

Total 25 raw suppliers

Chemical Property of 4-Methylthiazole-2-carbonitrile

Chemical Property:

Vapor Pressure:0.102mmHg at 25°C
Melting Point:34-39 °C
Refractive Index:1.558
Boiling Point:222.33 °C at 760 mmHg
PKA:-0.58±0.10(Predicted)
Flash Point:88.263 °C
PSA：64.92000
Density:1.256 g/cm³
LogP:1.32318
Storage Temp.:2-8°C
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:0
Exact Mass:124.00951931
Heavy Atom Count:8
Complexity:126

Purity/Quality:

99%, ^*data from raw suppliers

4-Methyl-2-thiazolecarbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn
Hazard Codes:Xn
Statements: 22-37/38-41
Safety Statements: 26-39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CSC(=N1)C#N

Technology Process of 4-Methylthiazole-2-carbonitrile

There total 3 articles about 4-Methylthiazole-2-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 298205-15-9
4-methyl-2-thiazolecarboxaldehyde oxime

: 100516-98-1
4-methyl-2-thiazollecarbonitrile

Guidance literature:: With pyridine; trifluoroacetic anhydride; In 1,4-dioxane; at 20 ℃; for 12h;
DOI:10.1021/jm0000719

Reference yield:

: 13750-68-0
4-methyl-thiazole-2-carbaldehyde

: 100516-98-1
4-methyl-2-thiazollecarbonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine; hydroxylamine hydrochloride / 16 h / 20 °C / Inert atmosphere

2: pyridine; trifluoroacetic anhydride / 1,4-dioxane / 16 h / -10 - 20 °C

With pyridine; hydroxylamine hydrochloride; trifluoroacetic anhydride; In 1,4-dioxane;