13750-68-0

Basic information

• Product Name: 4-METHYL-2-THIAZOLECARBOXALDEHYDE 97
• Synonyms: 4-METHYL-2-THIAZOLECARBOXALDEHYDE 97;4-Methyl-1,3-thiazole-2-carboxaldehyde;4-METHYL-2-THIAZOLYLCARBOXALDEHYDE, 97%;4-METHYL-1,3-THIAZOLE-2-CARBALDEHYDE;2-Formyl-4-methyl-1,3-thiazole;4-Methylthiazol-2-carbaldehyde;4-Methyl-2-thiazolecarboxaldehyde;4-Methyl-2-thiazolecarboxaldehyde 97%
• CAS NO: 13750-68-0
• Molecular Formula: C₅H₅NOS
• Molecular Weight: 127.1643
• EINECS: 1312995-182-4
• Product Categories: Aldehydes;Thiazoles, Isothiazoles &Benzothiazoles;Heterocyclic Compounds;Thiazoles, Isothiazoles & Benzothiazoles;Building Blocks;Heterocyclic Building Blocks;Thiazoles;Building Blocks;C1 to C6;C3 to C7;Carbonyl Compounds;Chemical Synthesis;Heterocyclic Building Blocks;Organic Building Blocks
• Mol File: 13750-68-0.mol
• Article Data: 16

Chemical Properties

• Boiling Point: 72-74 °C9 mm Hg(lit.)
• Flash Point: 153 °F
• Appearance: /
• Density: 1.183 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.074mmHg at 25°C
• Refractive Index: n20/D 1.5600(lit.)
• PKA: 0.86±0.10(Predicted)
• CAS DataBase Reference: 4-METHYL-2-THIAZOLECARBOXALDEHYDE 97(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHYL-2-THIAZOLECARBOXALDEHYDE 97(13750-68-0)
• EPA Substance Registry System: 4-METHYL-2-THIAZOLECARBOXALDEHYDE 97(13750-68-0)

Safety Data

• Hazard Codes: Xn
• Statements: 22-36-43
• Safety Statements: 26-36/37
• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 13750-68-0(Hazardous Substances Data)

Usage

Description

4-METHYL-2-THIAZOLECARBOXALDEHYDE 97, also known as 4-Methylthiazole-2-carbaldehyde, is an organic compound belonging to the thiazole family. It is characterized by its unique chemical structure, which features a thiazole ring with a methyl group at the 4th position and a formyl group at the 2nd position. 4-METHYL-2-THIAZOLECARBOXALDEHYDE 97 is known for its distinctive properties and potential applications in various industries.

Uses

Used in Pharmaceutical Industry:
4-METHYL-2-THIAZOLECARBOXALDEHYDE 97 is used as a key intermediate in the synthesis of selective cyclooxygenase-2 (COX-2) inhibitors. These inhibitors are important in the development of anti-inflammatory and pain-relieving medications. The thiazole-containing compounds, including 4-METHYL-2-THIAZOLECARBOXALDEHYDE 97, have demonstrated excellent oral activity, making them valuable in the pharmaceutical sector.
Used in Chemical Synthesis:
In the field of chemical synthesis, 4-METHYL-2-THIAZOLECARBOXALDEHYDE 97 serves as a versatile building block for the creation of various thiazole-based compounds. These compounds can be utilized in a wide range of applications, such as agrochemicals, dyes, and materials science. The unique properties of the thiazole ring make it an attractive candidate for the development of new molecules with potential applications in these industries.
Used in Flavor and Fragrance Industry:
4-METHYL-2-THIAZOLECARBOXALDEHYDE 97 is also used in the flavor and fragrance industry due to its characteristic odor and taste. The compound can be used to create unique and complex aromas for various applications, such as perfumes, cosmetics, and the food industry. Its ability to impart distinct sensory properties makes it a valuable asset in the development of new and innovative products in this sector.

InChI:InChI=1/C5H5NOS/c1-4-3-8-5(2-7)6-4/h2-3H,1H3

Upstream product

• 68-12-2 N,N-dimethyl-formamide 
• 89602-38-0 4-methyl-thiazole-2-yllithium 
• 693-95-8 4-Methylthiazole 
• 4394-85-8 4-morpholinecarboxaldehyde 
• 45534-10-9 2-ethenyl-4-methyl-1,3-thiazole 
• 7210-73-3 4-Methylthiazol-2-carbonsaeure-ethylester 
• 100516-76-5 4-methyl-1,3-thiazole-2-carbohydrazide 
• 541-58-2 2,4-dimethylthiazole 
• 103989-44-2 N-benzenesulfonyl-N'-(4-methyl-thiazole-2-carbonyl)-hydrazine 
• 24622-44-4 (E)-4-methyl-2-styrylthiazole 

Downstream Products

• 55152-99-3 6-(4-methyl-thiazol-2-yl)-dibenzo[d,f][1,3]diazepine-5,7-diol 
• 13750-70-4 N-(4-methyl-thiazol-2-yl-methylidene)-phenyl-amine 
• 143896-82-6 C₁₂H₁₃N₃O₂S₂ 
• 13750-63-5 (4-methylthiazol-2-yl)-methanol 
• 50398-72-6 2-(chloromethyl)-4-methylthiazole 
• 1061178-50-4 [(E)-1-(4-methylthiazol-2-yl)methylidene]-2,4,6-trimethylphenylamine 
• 1459695-50-1 C₂₆H₂₆F₅N₃O₂S 
• 1459695-70-5 C₁₂H₁₀F₃NOS 
• 1459695-71-6 C₁₂H₉ClF₃NS 
• 1459695-72-7 C₁₉H₁₃F₅N₂O₂S 
• 1459695-53-4 C₁₅H₁₇F₂N₃O₂S 

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