1,3-Dimethoxy-2-butyl-5-pentylbenzene

Base Information

• Chemical Name: 1,3-Dimethoxy-2-butyl-5-pentylbenzene
• CAS No.: 126838-67-3
• Molecular Formula: C₁₇H₂₈O₂
• Molecular Weight: 264.408
• Mol file: 126838-67-3.mol

Synonyms:1,3-Dimethoxy-2-butyl-5-pentylbenzene

Chemical Property of 1,3-Dimethoxy-2-butyl-5-pentylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,3-Dimethoxy-2-butyl-5-pentylbenzene

There total 7 articles about 1,3-Dimethoxy-2-butyl-5-pentylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-(4-Butyl-3,5-dimethoxy-phenyl)-pentan-1-ol (129589-58-8) → 1,3-Dimethoxy-2-butyl-5-pentylbenzene (126838-67-3)

Guidance literature:

With palladium on activated charcoal; ammonium formate; In acetic acid; for 36h; Heating;

DOI:10.1055/s-1990-26861

Reference yield:

3,4,5-trimethoxybenzaldehyde dimethyl acetal (59276-37-8) → 1,3-Dimethoxy-2-butyl-5-pentylbenzene (126838-67-3)

Guidance literature:

Multi-step reaction with 3 steps

1: 86 percent / 1) Na, 2) 1N HCl / tetrahydrofuran / 53 h / Ambient temperature

2: 89 percent / diethyl ether / 12 h / Ambient temperature

3: 92 percent / HCO₂NH₄, 10percent Pd-C / acetic acid / 36 h / Heating

With hydrogenchloride; palladium on activated charcoal; ammonium formate; sodium; In tetrahydrofuran; diethyl ether; acetic acid;

DOI:10.1055/s-1990-26861

Reference yield:

4-butyl-3,5-dimethoxybenzaldehyde (129589-56-6) → 1,3-Dimethoxy-2-butyl-5-pentylbenzene (126838-67-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / diethyl ether / 12 h / Ambient temperature

2: 92 percent / HCO₂NH₄, 10percent Pd-C / acetic acid / 36 h / Heating

With palladium on activated charcoal; ammonium formate; In diethyl ether; acetic acid;

DOI:10.1055/s-1990-26861

upstream raw materials:

1-bromo-butane

1-n-pentyl-3,4,5-trimethoxybenzene

1-(4-Butyl-3,5-dimethoxy-phenyl)-pentan-1-ol

1,3-dimethoxy-5-pentylbenzene

Downstream raw materials:

stemphol [2-butyl-5-pentylbenzene-1,3-diol]

Refernces

• 1、 Azzena, Ugo,Cossu, Sergio,Denurra, Teresa,Melloni, Giovanni,Piroddi, Anna Maria. "Regioselective Reductive Alkylation of 3,4,5-Trimethoxybenzaldehyde Dimethylacetal: A New Synthesis of 4-Alkyl-3,5-dimethoxybenzaldehydes and 2,5-Dialkyl-1,3-dimethoxybenzenes". . p. 313 - 314. Retrieved 2007/10/02.