N-(3'-deoxy-5'-O-triphenylmethyl-β-D-thymidin-3'-yl)-N'-(4-chloro-3-trifluoromethylphenyl)-guanidine

Base Information

• Chemical Name: N-(3'-deoxy-5'-O-triphenylmethyl-β-D-thymidin-3'-yl)-N'-(4-chloro-3-trifluoromethylphenyl)-guanidine
• CAS No.: 1271302-24-9
• Molecular Formula: C₃₇H₃₃ClF₃N₅O₄
• Molecular Weight: 704.148

Synonyms:N-(3'-deoxy-5'-O-triphenylmethyl-β-D-thymidin-3'-yl)-N'-(4-chloro-3-trifluoromethylphenyl)-guanidine

Chemical Property of N-(3'-deoxy-5'-O-triphenylmethyl-β-D-thymidin-3'-yl)-N'-(4-chloro-3-trifluoromethylphenyl)-guanidine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(3'-deoxy-5'-O-triphenylmethyl-β-D-thymidin-3'-yl)-N'-(4-chloro-3-trifluoromethylphenyl)-guanidine

There total 3 articles about N-(3'-deoxy-5'-O-triphenylmethyl-β-D-thymidin-3'-yl)-N'-(4-chloro-3-trifluoromethylphenyl)-guanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

1-(3'-deoxy-5'-O-triphenylmethyl-β-D-thymidin-3'-yl)-3-(4-chloro-3-(trifluoromethyl)phenyl)thiourea (1219808-55-5) → N-(3'-deoxy-5'-O-triphenylmethyl-β-D-thymidin-3'-yl)-N'-(4-chloro-3-trifluoromethylphenyl)-guanidine (1271302-24-9)

Guidance literature:

With ammonia; triethylamine; mercury dichloride; In N,N-dimethyl-formamide; at 0 - 20 ℃; Inert atmosphere;

DOI:10.1039/c0ob00591f

Reference yield:

3'-amino-3'-deoxy-5'-O-triphenylmethyl-β-D-thymidine (124355-25-5) → N-(3'-deoxy-5'-O-triphenylmethyl-β-D-thymidin-3'-yl)-N'-(4-chloro-3-trifluoromethylphenyl)-guanidine (1271302-24-9)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

2: ammonia; triethylamine; mercury dichloride / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

With ammonia; triethylamine; mercury dichloride; In N,N-dimethyl-formamide;

DOI:10.1039/c0ob00591f

Reference yield:

1-chloro-4-isothiocyanato-2-(trifluoromethyl)benzene (23163-86-2) → N-(3'-deoxy-5'-O-triphenylmethyl-β-D-thymidin-3'-yl)-N'-(4-chloro-3-trifluoromethylphenyl)-guanidine (1271302-24-9)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

2: ammonia; triethylamine; mercury dichloride / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

With ammonia; triethylamine; mercury dichloride; In N,N-dimethyl-formamide;

DOI:10.1039/c0ob00591f

upstream raw materials:

1-(3'-deoxy-5'-O-triphenylmethyl-β-D-thymidin-3'-yl)-3-(4-chloro-3-(trifluoromethyl)phenyl)thiourea

3'-amino-3'-deoxy-5'-O-triphenylmethyl-β-D-thymidine

1-chloro-4-isothiocyanato-2-(trifluoromethyl)benzene

Downstream raw materials:

N-(3'-deoxy-β-D-thymidin-3'-yl)-N'-(4-chloro-3-trifluoromethylphenyl)-guanidine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1271302-24-9 N-(3'-deoxy-5'-O-triphenylmethyl-β-D-thymidin-3'-yl)-N'-(4-chloro-3-trifluoromethylphenyl)-guanidine

Send

Send

Metric Ton KG G Pound L ML

Send

Send