1-benzyl-1',3-dimethyl-3'-phenylspiro(imidazolidine-4,4'-quinazoline)-2,2',5-trione

Base Information

Chemical Name:1-benzyl-1',3-dimethyl-3'-phenylspiro(imidazolidine-4,4'-quinazoline)-2,2',5-trione
CAS No.:1038397-04-4
Molecular Formula:C₂₅H₂₂N₄O₃
Molecular Weight:426.475
Hs Code.:

Synonyms:1-benzyl-1',3-dimethyl-3'-phenylspiro(imidazolidine-4,4'-quinazoline)-2,2',5-trione

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Chemical Property of 1-benzyl-1',3-dimethyl-3'-phenylspiro(imidazolidine-4,4'-quinazoline)-2,2',5-trione

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Technology Process of 1-benzyl-1',3-dimethyl-3'-phenylspiro(imidazolidine-4,4'-quinazoline)-2,2',5-trione

There total 1 articles about 1-benzyl-1',3-dimethyl-3'-phenylspiro(imidazolidine-4,4'-quinazoline)-2,2',5-trione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 100-39-0
benzyl bromide

: 107583-03-9
3'-Phenylspiro-2,2',5(3'H)-trione

: 74-88-4
methyl iodide

: 1038397-04-4
1-benzyl-1',3-dimethyl-3'-phenylspiro(imidazolidine-4,4'-quinazoline)-2,2',5-trione

Guidance literature:: benzyl bromide; 3'-Phenylspiro-2,2',5(3'H)-trione; With potassium hydroxide; In ethanol; for 4h; Heating;

With potassium carbonate; 18-crown-6 ether; potassium iodide; In toluene; for 0.25h;

methyl iodide; In toluene; for 24h; Further stages.; Heating;
DOI:10.1055/s-2008-1067032