methyl 5-amino-1-[(dimethylamino)sulfonyl]-2-[(4-morpholin-4-ylbenzyl)amino]-1H-benzimidazole-6-carboxylate

Base Information

Chemical Name:methyl 5-amino-1-[(dimethylamino)sulfonyl]-2-[(4-morpholin-4-ylbenzyl)amino]-1H-benzimidazole-6-carboxylate
CAS No.:1001242-94-9
Molecular Formula:C₂₂H₂₈N₆O₅S
Molecular Weight:488.568
Hs Code.:

Synonyms:methyl 5-amino-1-[(dimethylamino)sulfonyl]-2-[(4-morpholin-4-ylbenzyl)amino]-1H-benzimidazole-6-carboxylate

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Chemical Property of methyl 5-amino-1-[(dimethylamino)sulfonyl]-2-[(4-morpholin-4-ylbenzyl)amino]-1H-benzimidazole-6-carboxylate

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Technology Process of methyl 5-amino-1-[(dimethylamino)sulfonyl]-2-[(4-morpholin-4-ylbenzyl)amino]-1H-benzimidazole-6-carboxylate

There total 1 articles about methyl 5-amino-1-[(dimethylamino)sulfonyl]-2-[(4-morpholin-4-ylbenzyl)amino]-1H-benzimidazole-6-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1001242-93-8
methyl 1-[(dimethylamino)sulfonyl]-2-[(4-morpholin-4-ylbenzyl)amino]-5-nitro-1H-benzimidazole-6-carboxylate

: 1001242-94-9
methyl 5-amino-1-[(dimethylamino)sulfonyl]-2-[(4-morpholin-4-ylbenzyl)amino]-1H-benzimidazole-6-carboxylate

Guidance literature:: With acetic acid; zinc; In water; at 25 ℃; for 0.333333h;
DOI:10.1002/anie.200702961

Reference yield:

: 1001242-94-9
methyl 5-amino-1-[(dimethylamino)sulfonyl]-2-[(4-morpholin-4-ylbenzyl)amino]-1H-benzimidazole-6-carboxylate

: 29671-92-9
chloroformamidine hydrochloride

: 1001242-95-0
C₂₀H₂₁N₇O₂

Guidance literature:: methyl 5-amino-1-[(dimethylamino)sulfonyl]-2-[(4-morpholin-4-ylbenzyl)amino]-1H-benzimidazole-6-carboxylate; chloroformamidine hydrochloride; With dimethylsulfone; at 150 ℃; for 3h;

With ammonium hydroxide; at 25 ℃; Further stages.;
DOI:10.1002/anie.200702961