13-Ethyl-17-hydroxy-18,19-dinorpregn-5(10)-en-20-yn-3-one

Base Information

Chemical Name:13-Ethyl-17-hydroxy-18,19-dinorpregn-5(10)-en-20-yn-3-one
CAS No.:19914-67-1
Molecular Formula:C₂₁H₂₈O₂
Molecular Weight:312.452
Hs Code.:
Mol file:19914-67-1.mol

Synonyms:18,19-Dinor-17a-pregn-5(10)-en-20-yn-3-one,13-ethyl-17-hydroxy- (7CI,8CI); 13-Ethyl-17a-ethynyl-17-hydroxygon-5(10)-en-3-one

Suppliers and Price of 13-Ethyl-17-hydroxy-18,19-dinorpregn-5(10)-en-20-yn-3-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
Levonorgestrel impurity B European Pharmacopoeia (EP) Reference Standard
y0001379
$ 190.00

Biosynth Carbosynth
13-Ethyl-17-hydroxy-18,19-dinor-17a-pregn-5(10)-en-20-yn-3-one - EP
10 mg
$ 1528.80

Biosynth Carbosynth
13-Ethyl-17-hydroxy-18,19-dinor-17a-pregn-5(10)-en-20-yn-3-one - EP
5 mg
$ 840.90

Biosynth Carbosynth
13-Ethyl-17-hydroxy-18,19-dinor-17a-pregn-5(10)-en-20-yn-3-one - EP
2 mg
$ 462.50

Biosynth Carbosynth
13-Ethyl-17-hydroxy-18,19-dinor-17a-pregn-5(10)-en-20-yn-3-one - EP
1 mg
$ 254.40

Total 12 raw suppliers

Chemical Property of 13-Ethyl-17-hydroxy-18,19-dinorpregn-5(10)-en-20-yn-3-one

Chemical Property:

Melting Point:169-171?C
Refractive Index:1.572
Boiling Point:454.0±45.0 °C(Predicted)
PKA:13.10±0.40(Predicted)
PSA：37.30000
Density:1.14±0.1 g/cm3(Predicted)
LogP:4.14970
Storage Temp.:Refrigerator

Purity/Quality:

99%, ^*data from raw suppliers

Levonorgestrel impurity B European Pharmacopoeia (EP) Reference Standard ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses EP Levonorgestrel impurity B

Technology Process of 13-Ethyl-17-hydroxy-18,19-dinorpregn-5(10)-en-20-yn-3-one

There total 11 articles about 13-Ethyl-17-hydroxy-18,19-dinorpregn-5(10)-en-20-yn-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 848-07-7
(+/-)-13-ethyl-3-methoxygona-1,3,5⁽¹⁰⁾,8,14-pentaen-17-one

: 1095-74-5,5541-87-7,5772-36-1,19914-67-1
(+/-)13β-Ethyl-17α-ethynyl-17β-hydroxy-8-isogon-5(10)-en-3-one

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / Pd-C / methanol

2: NaBH₄ / ethanol

3: Li, liq. NH₃, EtOH / tetrahydrofuran

4: (i) Al(OiPr)3, cyclohexanone, toluene, (ii) /BRN= 906677/, Li, H₂NCH₂CH₂NH₂, AcNMe₂, (iii) aq. oxalic acid, MeOH

With sodium tetrahydroborate; ethanol; ammonia; hydrogen; lithium; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol;
DOI:10.1021/jm00321a016

Reference yield:

: (+/-)-13-ethyl-3-methoxygona-1,3,5⁽¹⁰⁾,8-tetraen-17-one

: 1095-74-5,5541-87-7,5772-36-1,19914-67-1
(+/-)13β-Ethyl-17α-ethynyl-17β-hydroxy-8-isogon-5(10)-en-3-one

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / Pd-C / methanol; tetrahydrofuran

2: NaBH₄ / ethanol

3: Li, liq. NH₃, EtOH / tetrahydrofuran

4: (i) Al(OiPr)3, cyclohexanone, toluene, (ii) /BRN= 906677/, Li, H₂NCH₂CH₂NH₂, AcNMe₂, (iii) aq. oxalic acid, MeOH

With sodium tetrahydroborate; ethanol; ammonia; hydrogen; lithium; palladium on activated charcoal; In tetrahydrofuran; methanol; ethanol;
DOI:10.1021/jm00321a016

Reference yield:

: 848-04-4,968-74-1,2445-28-5,5914-87-4,6161-35-9,7373-93-5,7434-80-2,17092-07-8,19301-69-0,31266-48-5,107598-32-3
(+/-)-13-ethyl-3-methoxy-8α-gona-1,3,5(10)-trien-17-one

: 1095-74-5,5541-87-7,5772-36-1,19914-67-1
(+/-)13β-Ethyl-17α-ethynyl-17β-hydroxy-8-isogon-5(10)-en-3-one

Guidance literature:: Multi-step reaction with 3 steps

1: NaBH₄ / ethanol

2: Li, liq. NH₃, EtOH / tetrahydrofuran

3: (i) Al(OiPr)3, cyclohexanone, toluene, (ii) /BRN= 906677/, Li, H₂NCH₂CH₂NH₂, AcNMe₂, (iii) aq. oxalic acid, MeOH

With sodium tetrahydroborate; ethanol; ammonia; lithium; In tetrahydrofuran; ethanol;
DOI:10.1021/jm00321a016