<6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl>-acetic acid-ethylester

Base Information

Chemical Name:<6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl>-acetic acid-ethylester
CAS No.:156897-46-0
Molecular Formula:C₂₃H₂₂ClNO₂
Molecular Weight:379.886
Hs Code.:

Synonyms:<6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl>-acetic acid-ethylester

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Chemical Property of <6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl>-acetic acid-ethylester

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Technology Process of <6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl>-acetic acid-ethylester

There total 6 articles about <6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl>-acetic acid-ethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 623-73-4
diazoacetic acid ethyl ester

: 104765-64-2
6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin

: 156897-46-0
<6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl>-acetic acid-ethylester

Guidance literature:: With copper; In toluene; for 0.25h; Heating;
DOI:10.1021/jm00038a021

Reference yield:

: 69311-30-4
5-benzyl-3,4-dihydro-2H-pyrrole

: 156897-46-0
<6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl>-acetic acid-ethylester

Guidance literature:: Multi-step reaction with 2 steps

1: NaHCO₃ / diethyl ether; ethanol; H₂O / 36 h / Ambient temperature

2: Cu / toluene / 0.25 h / Heating

With copper; sodium hydrogencarbonate; In diethyl ether; ethanol; water; toluene;
DOI:10.1021/jm00038a021

Reference yield:

: 536-38-9
4-chlorobenzoylmethyl bromide

: 156897-46-0
<6-(4-chlorophenyl)-7-phenyl-2,3-dihydro-1H-pyrrolizin-5-yl>-acetic acid-ethylester

Guidance literature:: Multi-step reaction with 2 steps

1: NaHCO₃ / diethyl ether; ethanol; H₂O / 36 h / Ambient temperature

2: Cu / toluene / 0.25 h / Heating

With copper; sodium hydrogencarbonate; In diethyl ether; ethanol; water; toluene;
DOI:10.1021/jm00038a021