methyl 4-(2,6-bis-{2-[2,5-dipropyloxy-4-(2-triisopropylsilylethynyl)phenyl]-ethynyl}-4-tert-butylphenoxy)-butyrate

Base Information

Chemical Name:methyl 4-(2,6-bis-{2-[2,5-dipropyloxy-4-(2-triisopropylsilylethynyl)phenyl]-ethynyl}-4-tert-butylphenoxy)-butyrate
CAS No.:642486-99-5
Molecular Formula:C₆₅H₉₄O₇Si₂
Molecular Weight:1043.63
Hs Code.:

Synonyms:methyl 4-(2,6-bis-{2-[2,5-dipropyloxy-4-(2-triisopropylsilylethynyl)phenyl]-ethynyl}-4-tert-butylphenoxy)-butyrate

Suppliers and Price of methyl 4-(2,6-bis-{2-[2,5-dipropyloxy-4-(2-triisopropylsilylethynyl)phenyl]-ethynyl}-4-tert-butylphenoxy)-butyrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 4-(2,6-bis-{2-[2,5-dipropyloxy-4-(2-triisopropylsilylethynyl)phenyl]-ethynyl}-4-tert-butylphenoxy)-butyrate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 4-(2,6-bis-{2-[2,5-dipropyloxy-4-(2-triisopropylsilylethynyl)phenyl]-ethynyl}-4-tert-butylphenoxy)-butyrate

There total 3 articles about methyl 4-(2,6-bis-{2-[2,5-dipropyloxy-4-(2-triisopropylsilylethynyl)phenyl]-ethynyl}-4-tert-butylphenoxy)-butyrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 221292-51-9
1,4-dipropyloxy-2-ethynyl-5-(2-triisopropylsilylethinyl)benzene

: 642486-98-4
methyl 4-(tert-butyl-2,6-diiodophenoxy)-butyrate

: 642486-99-5
methyl 4-(2,6-bis-{2-[2,5-dipropyloxy-4-(2-triisopropylsilylethynyl)phenyl]-ethynyl}-4-tert-butylphenoxy)-butyrate

Guidance literature:: With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; at 20 - 50 ℃; for 19h;
DOI:10.1016/j.tet.2003.09.045

Reference yield:

: 55444-67-2
trimethyl ortho-4-bromobutanoate

: 642486-99-5
methyl 4-(2,6-bis-{2-[2,5-dipropyloxy-4-(2-triisopropylsilylethynyl)phenyl]-ethynyl}-4-tert-butylphenoxy)-butyrate

Guidance literature:: Multi-step reaction with 2 steps

1: 57 percent / K₂CO₃; KI / dimethylformamide / 20 h / 60 °C

2: 94 percent / CuI; Et₃N / Pd(PPh₃)2Cl₂ / tetrahydrofuran / 19 h / 20 - 50 °C

With copper(l) iodide; potassium carbonate; triethylamine; potassium iodide; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; N,N-dimethyl-formamide; 2: Hagihara-Sonogashira coupling;
DOI:10.1016/j.tet.2003.09.045

Reference yield:

: 75908-75-7
2,6-diiodo-4-(tert-butyl)phenol

: 642486-99-5
methyl 4-(2,6-bis-{2-[2,5-dipropyloxy-4-(2-triisopropylsilylethynyl)phenyl]-ethynyl}-4-tert-butylphenoxy)-butyrate

Guidance literature:: Multi-step reaction with 2 steps

1: 57 percent / K₂CO₃; KI / dimethylformamide / 20 h / 60 °C

2: 94 percent / CuI; Et₃N / Pd(PPh₃)2Cl₂ / tetrahydrofuran / 19 h / 20 - 50 °C

With copper(l) iodide; potassium carbonate; triethylamine; potassium iodide; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; N,N-dimethyl-formamide; 2: Hagihara-Sonogashira coupling;
DOI:10.1016/j.tet.2003.09.045