55444-67-2

Basic information

• Product Name: 4-BROMO-1,1,1-TRIMETHOXYBUTANE
• Synonyms: 4-BROMO-1,1,1-TRIMETHOXYBUTANE;TRIMETHYL 4-BROMOORTHOBUTYRATE;Trimethyl 4-bromoorthobutyrate,4-Bromo-1,1,1-trimethoxybutane;Trimethyl 4-bromoorthobutyrate 95%
• CAS NO: 55444-67-2
• Molecular Formula: C₇H₁₅BrO₃
• Molecular Weight: 227.1
• Mol File: 55444-67-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 70 °C0.7 mm Hg(lit.)
• Flash Point: 163 °F
• Appearance: /
• Density: 1.309 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0271mmHg at 25°C
• Refractive Index: n20/D 1.456(lit.)
• Storage Temp.: 2-8°C
• Solubility: Dichloromethane
• CAS DataBase Reference: 4-BROMO-1,1,1-TRIMETHOXYBUTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMO-1,1,1-TRIMETHOXYBUTANE(55444-67-2)
• EPA Substance Registry System: 4-BROMO-1,1,1-TRIMETHOXYBUTANE(55444-67-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 55444-67-2(Hazardous Substances Data)

Usage

Uses

Trimethyl 4-bromoorthobutyrate is used in the synthesis of an intermediate of hydrophilic chemiluminescent acridinium esters containing N-sulfopropyl groups which are extremely useful labels in the clinical diagnostics industry especially in automated immunochemical analyzers such as Siemens Healthcare Diagnostics'' ADVIA Centaur systems.

InChI:InChI=1/C7H15BrO3/c1-9-7(10-2,11-3)5-4-6-8/h4-6H2,1-3H3

Upstream product

• 67-56-1 methanol 
• 21367-90-8 methyl-4-bromo-1-butane imidate hydrochloride 

Downstream Products

• 129152-22-3 3-(3-Carboxypropyl)-2-cyclohexenon-methylester 
• 642486-98-4 methyl 4-(tert-butyl-2,6-diiodophenoxy)-butyrate 
• 209688-77-7 4,4,4-trimethoxybutyl4-methylbenzenesulfonothioate 
• 1398274-06-0 methyl 4-(2-phenyl-1,3-dithian-2-yl)butanoate 
• 883245-09-8 2-(3-bromopropyl)benzooxazole 
• 1027731-82-3 (S)-9,9-dimethoxy-2,2-dimethyl-4-phenyl-10-oxa-λ⁴-thia-3-aza-2-silaundec-3-ene 4-oxide 
• 129152-28-9 4-(1-Hydroxy-cyclohex-2-enyl)-butyric acid methyl ester 
• 129152-23-4 4-(3-Hydroxy-cyclohex-1-enyl)-butyric acid methyl ester 
• 50781-91-4 methyl 7-hydroxy-5-heptynoate 
• 119950-78-6 3,6-di(4,4,4-trimethoxybutyl) phthalonitrile 
• 642487-03-4 methyl 4-{2,6-bis-[2-(2,5-dipropyloxy-4-{2-[2-(2-(S)-methylbutoxy)-3-(2-trimethylethynyl)-5-tert-butylphenyl]ethynyl}phenyl)ethynyl]-4-tert-butylphenoxy}-butyrate 
• 642487-04-5 methyl 4-{2,6-bis-[2-(2,5-dipropyloxy-4-{2-[2-(2-(S)-methylbutoxy)-3-ethynyl-5-tert-butylphenyl]ethynyl}phenyl)ethynyl]-4-tert-butylphenoxy}-butyrate 
• 642487-02-3 methyl 4-{2,6-bis-[2-(2,5-dipropyloxy-4-{2-[2-(2-(S)-methylbutoxy)-3-iodo-5-tert-butylphenyl]ethynyl}phenyl)ethynyl]-4-tert-butylphenoxy}-butyrate 
• 642486-99-5 methyl 4-(2,6-bis-{2-[2,5-dipropyloxy-4-(2-triisopropylsilylethynyl)phenyl]-ethynyl}-4-tert-butylphenoxy)-butyrate 

Relevant articles and documents

Enantioselective synthesis of methyl (+)-(R)-11-hydroxy-8(E)-dodecenoate, the seco-ester of (+)-(R)-recifeiolide, from [2(S), S(R)]-2-(p-tolylsulfinyl)methyl oxirane

A short and enantioselective synthesis of the seco-ester of (+)-(R)-recifeiolide from the readily available [2(S), S(R)]-2-(p-tolylsulfinyl)methyl oxirane is described.