Pyrimidine, 2-amino-5-(aminomethyl)-4-methyl- (8CI)

Base Information

• Chemical Name: Pyrimidine, 2-amino-5-(aminomethyl)-4-methyl- (8CI)
• CAS No.: 19594-45-7
• Molecular Formula: C₆H₁₀N₄
• Molecular Weight: 138.172
• Hs Code.: 2933599090
• Mol file: 19594-45-7.mol

Synonyms:Pyrimidine,2-amino-5-(aminomethyl)-4-methyl- (8CI);2-Amino-5-aminomethyl-4-methylpyrimidine

Chemical Property of Pyrimidine, 2-amino-5-(aminomethyl)-4-methyl- (8CI)

Chemical Property:

• PSA: 78.55000
• LogP: 0.45630

Purity/Quality:

99% ^*data from raw suppliers

5-(Aminomethyl)-4-methylpyrimidin-2-amine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Pyrimidine, 2-amino-5-(aminomethyl)-4-methyl- (8CI)

There total 2 articles about Pyrimidine, 2-amino-5-(aminomethyl)-4-methyl- (8CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-4-methylpyrimidine-5-carbonitrile (17321-97-0) → 5-aminomethyl-4-methyl-pyrimidin-2-ylamine (19594-45-7)

Guidance literature:

With methanol; ammonia; nickel; Hydrogenation;

DOI:10.1021/ja01209a019

Reference yield:

5-bromo-4-methylpyrimidine-2-ylamine (17321-93-6) → 5-aminomethyl-4-methyl-pyrimidin-2-ylamine (19594-45-7)

Guidance literature:

Multi-step reaction with 2 steps

2: Raney nickel; methanol; NH₃ / Hydrogenation

With methanol; ammonia; nickel;

DOI:10.1021/ja01209a019

upstream raw materials:

2-amino-4-methylpyrimidine-5-carbonitrile

5-bromo-4-methylpyrimidine-2-ylamine