(N-(Benzyloxycarbonyl)glycyl)-l-serine hydrazide

Base Information

• Chemical Name: (N-(Benzyloxycarbonyl)glycyl)-l-serine hydrazide
• CAS No.: 19526-00-2
• Molecular Formula: C13H18 N4 O5
• Molecular Weight: 0
• Mol file: 19526-00-2.mol

Synonyms:Serine,N-(N-carboxyglycyl)-, N-benzyl ester, hydrazide (6CI,7CI); Serine,N-(N-carboxyglycyl)-, N-benzyl ester, hydrazide, L- (8CI)

Chemical Property of (N-(Benzyloxycarbonyl)glycyl)-l-serine hydrazide

Chemical Property:

• PSA: 142.78000
• LogP: 0.25280

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (N-(Benzyloxycarbonyl)glycyl)-l-serine hydrazide

There total 6 articles about (N-(Benzyloxycarbonyl)glycyl)-l-serine hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(N-benzyloxycarbonyl-glycyl)-L-serine methyl ester (108849-83-8,10239-27-7) → Z-Gly-Ser-hydrazide (19526-00-2)

Guidance literature:

With hydrazine hydrate; In methanol;

DOI:10.1248/cpb.19.1315

Reference yield:

N-benzyloxycarbonylglycylserine (4180-62-5) → Z-Gly-Ser-hydrazide (19526-00-2)

Guidance literature:

Multistep reaction; (i) HCl, MeOH, (ii) N₂H₄*H₂O;

DOI:10.1021/ja00869a024

Reference yield:

N-(Benzyloxycarbonyl)glycine (1138-80-3) → Z-Gly-Ser-hydrazide (19526-00-2)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) N-methylmorpholine, THF, (ii) DCC, CH₂Cl₂

2: N₂H₄*H₂O / ethanol

With hydrazine hydrate; In ethanol;

upstream raw materials:

N-(N-benzyloxycarbonyl-glycyl)-L-serine methyl ester

N-benzyloxycarbonylglycylserine

N-(Benzyloxycarbonyl)glycine

benzyloxycarbonyl-Gly-Ser-OMe

Refernces