Technology Process of C22H24N4O3
There total 7 articles about C22H24N4O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
diethyl 1-cyanomethylphosphonate;
With
sodium hydride;
In
1,2-dimethoxyethane;
at 0 ℃;
for 0.333333h;
Inert atmosphere;
C20H23N3O4;
In
1,2-dimethoxyethane;
at 0 - 30 ℃;
for 2.5h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium azide / water; acetone / 16 h / 50 °C / Large scale
1.2: 1 h / Large scale
2.1: hydrogenchloride / ethanol / 5 h / 83 °C / Large scale
3.1: sodium hydride / N,N-dimethyl-formamide / 0.75 h / -25 °C / Inert atmosphere
3.2: 2.2 h / 25 °C / Inert atmosphere
4.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran / 3.5 h / -20 - 30 °C / Inert atmosphere
5.1: sodium hydride / 1,2-dimethoxyethane / 0.33 h / 0 °C / Inert atmosphere
5.2: 2.5 h / 0 - 30 °C / Inert atmosphere
With
hydrogenchloride; sodium azide; sodium hydride; lithium tri-t-butoxyaluminum hydride;
In
tetrahydrofuran; 1,2-dimethoxyethane; ethanol; water; N,N-dimethyl-formamide; acetone;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sodium hydride / N,N-dimethyl-formamide / 0.75 h / -25 °C / Inert atmosphere
1.2: 2.2 h / 25 °C / Inert atmosphere
2.1: lithium tri-t-butoxyaluminum hydride / tetrahydrofuran / 3.5 h / -20 - 30 °C / Inert atmosphere
3.1: sodium hydride / 1,2-dimethoxyethane / 0.33 h / 0 °C / Inert atmosphere
3.2: 2.5 h / 0 - 30 °C / Inert atmosphere
With
sodium hydride; lithium tri-t-butoxyaluminum hydride;
In
tetrahydrofuran; 1,2-dimethoxyethane; N,N-dimethyl-formamide;
