879551-01-6Relevant articles and documents
BI- AND MONOCYCLIC NUCLEOSIDE ANALOGS FOR TREATMENT OF HEPATITIS E
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, (2021/10/22)
The present disclosure is directed toward bi- and monocyclic nucleoside analogs, and compositions comprising these compounds for use in the treatment of hepatitis E infections.
METHOD FOR PRODUCING CYCLIC SULFATE
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Paragraph 0057; 0058; 0059; 0060; 0061, (2017/09/12)
PROBLEM TO BE SOLVED: To provide an efficient method for producing a cyclic sulfate that is useful as an intermediate for pharmaceuticals and agrochemicals. SOLUTION: The cyclic sulfate can be produced by reacting a starting material, 1,2-diols, with sulfuryl halide in the presence of an inorganic base. Further, it was favorably found that by reacting sulfuryl halide to 1,2-diols under specific conditions, the target material of the present invention, the cyclic sulfate, can be isolated in high selectivity. The present invention enables production of a cyclic sulfate, which has been a little difficult to isolate, in high productivity by one step by a simple work. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT
SUBSTITUTED NUCLEOSIDES, NUCLEOTIDES AND ANALOGS THEREOF
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, (2016/03/11)
Disclosed herein are nucleosides, nucleotide analogs, methods of synthesizing nucleotide analogs and methods of treating diseases and/or conditions such as a Filoviridae virus infection with one or more nucleosides and/or nucleotide analogs.