Technology Process of benzyl o-methylsulfonylphenyl sulfide
There total 4 articles about benzyl o-methylsulfonylphenyl sulfide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
phenylmethanethiol;
With
sodium methylate;
In
methanol;
o-chlorophenyl methyl sulfone;
In
dimethyl sulfoxide;
at 20 ℃;
for 19h;
DOI:10.1071/ch99139
- Guidance literature:
-
o-chlorophenyl methyl sulfone; sodium benzylmercaptide;
In
dimethyl sulfoxide;
at 20 ℃;
for 19h;
With
hydrogenchloride;
In
water; dimethyl sulfoxide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 85 percent / NaOMe / methanol / 24 h / 20 °C
2.1: 81 percent / aq. H2SO4; KMnO4 / CHCl3 / 1 h / 20 °C
3.1: NaOMe / methanol
3.2: 55 percent / dimethylsulfoxide / 19 h / 20 °C
With
potassium permanganate; sulfuric acid; sodium methylate;
In
methanol; chloroform;
1.1: Methylation / 2.1: Oxidation / 3.1: salt formation / 3.2: Substitution;
DOI:10.1071/ch99139
