4-ETHYLBENZHYDROL

Base Information

• Chemical Name: 4-ETHYLBENZHYDROL
• CAS No.: 22543-70-0
• Molecular Formula: C₁₅H₁₆O
• Molecular Weight: 212.291
• Mol file: 22543-70-0.mol

Synonyms:α-(p-ethylphenyl)-α-phenylmethanol

Chemical Property of 4-ETHYLBENZHYDROL

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

4-ETHYLBENZHYDROL ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-ETHYLBENZHYDROL

There total 7 articles about 4-ETHYLBENZHYDROL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

trimethyl(phenyl)stannane (934-56-5) + 4-ethylbenzylaldehyde (4748-78-1) → α-(p-ethylphenyl)-α-phenylmethanol (22543-70-0)

Guidance literature:

With rhodium(I)-bis(1,5-cyclooctadiene) tetrafluoroborate; In water; at 110 ℃; for 12h;

DOI:10.1021/ja001699b

Reference yield:

4-ethylbenzophenone (18220-90-1) → α-(p-ethylphenyl)-α-phenylmethanol (22543-70-0)

Guidance literature:

With diethyl ether; ethanol; benzene; weiteres Reagens: Natrium-Amalgam;

DOI:10.1021/jo01164a023

Reference yield:

benzaldehyde (100-52-7) → α-(p-ethylphenyl)-α-phenylmethanol (22543-70-0)

Guidance literature:

With diethyl ether;

DOI:10.1021/ja01649a030

upstream raw materials:

4-ethylbenzophenone

benzaldehyde

trimethyl(phenyl)stannane

4-ethylbenzylaldehyde

Downstream raw materials:

C₁₅H₁₄O₃

4-ethylbenzophenone

4-acetylbenzophenone

(4-acetylphenyl)(phenyl)methanol

Refernces

• 1、 Li, Chao-Jun,Meng, Yue. "Grignard-type carbonyl phenylation in water and under an air atmosphere [1]". . p. 9538 - 9539. Retrieved 2007/10/03.