2-Butanone,4-(1H-benzimidazol-2-yl)-(9CI)

Base Information

• Chemical Name: 2-Butanone,4-(1H-benzimidazol-2-yl)-(9CI)
• CAS No.: 19276-01-8
• Molecular Formula: C₁₁H₁₂N₂O
• Molecular Weight: 188.229
• Hs Code.: 2933990090
• Mol file: 19276-01-8.mol

Synonyms:2-Butanone,4-(2-benzimidazolyl)- (8CI); 2-(g-Oxybutyl)benzimidazole

Chemical Property of 2-Butanone,4-(1H-benzimidazol-2-yl)-(9CI)

Chemical Property:

• PSA: 45.75000
• LogP: 2.08450

Purity/Quality:

99.0% MIN ^*data from raw suppliers

2-BUTANONE, 4-(1H-BENZIMIDAZOL-2-YL)- 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Butanone,4-(1H-benzimidazol-2-yl)-(9CI)

There total 4 articles about 2-Butanone,4-(1H-benzimidazol-2-yl)-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-chloromethyl-1H-benzimidazole (4857-04-9) + acetylacetone (123-54-6,81235-32-7) → 2-acetyl-3-methylpyrrolo<1,2-a>benzimidazole (152037-49-5) + 2-(γ-Oxo-butyl)-benzimidazol (19276-01-8) + 3-[(1H-benzimidazol-2-yl)methyl]pentane-2,4-dione (397869-09-9)

Guidance literature:

With N-benzyl-N,N,N-triethylammonium chloride; sodium carbonate; In 1,4-dioxane; water; Title compound not separated from byproducts;

DOI:10.1007/BF01176967

Reference yield: 75.0%

2-hydroxy-2-methylcyclobutan-1-one (25733-27-1) + 1,2-diamino-benzene (95-54-5) → 2-(γ-Oxo-butyl)-benzimidazol (19276-01-8)

Guidance literature:

In toluene; at 20 ℃; for 48h;

DOI:10.1002/adsc.202000541

Reference yield:

levulinic acid (123-76-2) + 1,2-diamino-benzene (95-54-5) → 2-(γ-Oxo-butyl)-benzimidazol (19276-01-8)

Guidance literature:

With hydrogenchloride; In water; for 18h; Heating / reflux;

upstream raw materials:

2-chloromethyl-1H-benzimidazole

acetylacetone

levulinic acid

1,2-diamino-benzene