Methyl 2-(3-chlorophenyl)-2-hydroxyacetate

Base Information

Chemical Name:Methyl 2-(3-chlorophenyl)-2-hydroxyacetate
CAS No.:13305-18-5
Molecular Formula:C₉H₉ClO₃
Molecular Weight:200.622
Hs Code.:2918199890
European Community (EC) Number:958-538-5
Nikkaji Number:J2.932.598G

Synonyms:methyl 2-(3-chlorophenyl)-2-hydroxyacetate;13305-18-5;MFCD16693824;methyl (3-chlorophenyl)(hydroxy)acetate;SCHEMBL1525273;AKOS011496497;AT40870;SB48218;BS-12266;SY189324;methyl2-(3-chlorophenyl)-2-hydroxyacetate;CS-0217564;EN300-77542;Z965047532

Suppliers and Price of Methyl 2-(3-chlorophenyl)-2-hydroxyacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
methyl2-(3-chlorophenyl)-2-hydroxyacetate
25mg
$ 45.00

AK Scientific
methyl(3-chlorophenyl)(hydroxy)acetate
20mg
$ 89.00

Total 3 raw suppliers

Chemical Property of Methyl 2-(3-chlorophenyl)-2-hydroxyacetate

Chemical Property:

Melting Point:84 °C
Boiling Point:296.0±25.0 °C(Predicted)
Density:1.316±0.06 g/cm3(Predicted)
XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:200.0240218
Heavy Atom Count:13
Complexity:184

Purity/Quality:

95% ^*data from raw suppliers

methyl2-(3-chlorophenyl)-2-hydroxyacetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C(C1=CC(=CC=C1)Cl)O

Technology Process of Methyl 2-(3-chlorophenyl)-2-hydroxyacetate

There total 7 articles about Methyl 2-(3-chlorophenyl)-2-hydroxyacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.5%

: 13305-18-5
(3-chlorophenyl)hydroxyacetic acid methyl ester

Guidance literature:

Reference yield: 97.0%

: 67-56-1
methanol

: 16273-37-3,32222-43-8,52950-16-0,61008-98-8
3-chloromandelic acid

: 13305-18-5
(3-chlorophenyl)hydroxyacetic acid methyl ester

Guidance literature:: With sulfuric acid; at 60 ℃;
DOI:10.1016/j.bmcl.2018.01.059

Reference yield: 95.0%

: 34966-50-2
methyl 2-(3-chlorophenyl)-2-oxoacetate

: 13305-18-5
(3-chlorophenyl)hydroxyacetic acid methyl ester

Guidance literature:: With methanol; benzaldehyde; 1,3-bis(mesityl)imidazolium chloride; triethylamine; at 25 ℃; for 5h; regioselective reaction; Inert atmosphere;
DOI:10.1016/j.tetlet.2010.12.022