(E)-methyl 2-[(3-tert-butyldimethylsilyloxy-4-methoxyphenyl)propenoylamino]-3-oxobutanoate

Base Information

• Chemical Name: (E)-methyl 2-[(3-tert-butyldimethylsilyloxy-4-methoxyphenyl)propenoylamino]-3-oxobutanoate
• CAS No.: 938071-26-2
• Molecular Formula: C₂₁H₃₁NO₆Si
• Molecular Weight: 421.566

Synonyms:(E)-methyl 2-[(3-tert-butyldimethylsilyloxy-4-methoxyphenyl)propenoylamino]-3-oxobutanoate

Chemical Property of (E)-methyl 2-[(3-tert-butyldimethylsilyloxy-4-methoxyphenyl)propenoylamino]-3-oxobutanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-methyl 2-[(3-tert-butyldimethylsilyloxy-4-methoxyphenyl)propenoylamino]-3-oxobutanoate

There total 3 articles about (E)-methyl 2-[(3-tert-butyldimethylsilyloxy-4-methoxyphenyl)propenoylamino]-3-oxobutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(E)-3-(3-tert-butyldimethylsiloxy-4-methoxyphenyl)acrylamide (938071-25-1) + 2-Diazo-3-oxo-butyric acid methyl ester (24762-04-7) → (E)-methyl 2-[(3-tert-butyldimethylsilyloxy-4-methoxyphenyl)propenoylamino]-3-oxobutanoate (938071-26-2)

Guidance literature:

dirhodium tetraacetate; In dichloromethane; for 4h; Heating;

DOI:10.1039/b618160k

Reference yield:

3-hydroxy-4-methoxycinnamamide → (E)-methyl 2-[(3-tert-butyldimethylsilyloxy-4-methoxyphenyl)propenoylamino]-3-oxobutanoate (938071-26-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / imidazole / dimethylformamide

2: 90 percent / dirhodium tetraacetate / CH₂Cl₂ / 4 h / Heating

With 1H-imidazole; dirhodium tetraacetate; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/b618160k

Reference yield:

tert-butyldimethylsilyl chloride (18162-48-6) → (E)-methyl 2-[(3-tert-butyldimethylsilyloxy-4-methoxyphenyl)propenoylamino]-3-oxobutanoate (938071-26-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 70 percent / imidazole / dimethylformamide

2: 90 percent / dirhodium tetraacetate / CH₂Cl₂ / 4 h / Heating

With 1H-imidazole; dirhodium tetraacetate; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1039/b618160k

upstream raw materials:

(E)-3-(3-tert-butyldimethylsiloxy-4-methoxyphenyl)acrylamide

2-Diazo-3-oxo-butyric acid methyl ester

tert-butyldimethylsilyl chloride

Downstream raw materials:

methyl 2-(3-tert-butyldimethylsilyloxy-4-methoxystyryl)-5-methyloxazole-4-carboxylate

methyl 2-[2-(2-(3-tert-butyldimethylsiloxy-4-methoxystyryl)-5-methyloxazol-4-yl)]-(2-hydroxyethyl)-5-methyloxazole-4-carboxylate

methyl 2-[2-(2-(3-tert-butyldimethylsiloxy-4-methoxystyryl)-5-methyloxazol-4-yl)]-(2-oxoethyl)-5-methyloxazole-4-carboxylate

C₃₁H₃₉N₃O₆Si

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 938071-26-2 (E)-methyl 2-[(3-tert-butyldimethylsilyloxy-4-methoxyphenyl)propenoylamino]-3-oxobutanoate

Send

Send

Metric Ton KG G Pound L ML

Send

Send