1H-PYRAZOL-5-AMINE

Base Information

• Chemical Name: 1H-PYRAZOL-5-AMINE
• CAS No.: 1225387-53-0
• Molecular Formula: C₃H₅N₃
• Molecular Weight: 83.0928
• Mol file: 1225387-53-0.mol

Synonyms:3⁽⁵⁾-aminopyrazole

Chemical Property of 1H-PYRAZOL-5-AMINE

Chemical Property:

• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

98%,99%, ^*data from raw suppliers

3H-pyrazol-3-amine 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-PYRAZOL-5-AMINE

There total 7 articles about 1H-PYRAZOL-5-AMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

6-Nitro-4H-pyrazolo[1,5-a]pyrimidin-7-one (106087-63-2) → 4-nitro-3-pyrazolone hydrazinium salt (137811-92-8) + 3(5)-aminopyrazole (1225387-53-0)

Guidance literature:

With hydrazine hydrate; In isopropyl alcohol; for 0.5h; Heating;

DOI:10.1007/BF00474001

Reference yield: 33.0%

N-aminopyrazole (3994-46-5) → 3(5)-aminopyrazole (1225387-53-0)

Guidance literature:

With hydrogen bromide; at 140 ℃; for 14h;

DOI:10.1039/P19900000809

Reference yield:

3-dimethylaminoacrylonitrile (2407-68-3) → 3(5)-aminopyrazole (1225387-53-0)

Guidance literature:

With hydrazine monohydrobromide; In ethanol; water; at 110 ℃; for 5h;

DOI:10.1016/j.bmcl.2008.06.052

upstream raw materials:

N-aminopyrazole

6-Nitro-4H-pyrazolo[1,5-a]pyrimidin-7-one

5-nitro-1H-pyrazole

acetonitrile

Downstream raw materials:

5-methyl-4H-pyrazolo<1,5-a>pyrimidin-7-one

7-Amino-5-phenylpyrazole<1,5-a>pyrimidine

5-phenyl-4H-pyrazolo<1,5-a>pyrimidin-7-one

3-Amino-N-phenyl-1H-pyrazol-1-carboxamid

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