1-(nitromethyl)-2-(4′-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline

Base Information

• Chemical Name: 1-(nitromethyl)-2-(4′-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline
• CAS No.: 1132765-76-4
• Molecular Formula: C₁₆H₁₅N₃O₄
• Molecular Weight: 313.313
• Mol file: 1132765-76-4.mol

Synonyms:1-(nitromethyl)-2-(4′-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline

Chemical Property of 1-(nitromethyl)-2-(4′-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 1-(nitromethyl)-2-(4′-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline

There total 1 articles about 1-(nitromethyl)-2-(4′-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

nitromethane (75-52-5) + 2-(4′-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline (93733-03-0) → 1-(nitromethyl)-2-(4′-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline (1132765-76-4)

Guidance literature:

With oxygen; In methanol; at 60 ℃; for 8h;

DOI:10.1039/c6cy02567f

Reference yield: 46.0%

1-(nitromethyl)-2-(4′-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline (1132765-76-4) → 2-(4-nitrophenyl)-3,4-dihydroisoquinolin-1(2H)-one (127827-48-9)

Guidance literature:

With potassium phosphate; 1-amino-9,10-anthracenedione; In acetonitrile; at 20 ℃; for 48h; Irradiation;

DOI:10.1002/chem.201500612

upstream raw materials:

nitromethane

2-(4′-nitrophenyl)-1,2,3,4-tetrahydroisoquinoline

Downstream raw materials:

2-(4-nitrophenyl)-3,4-dihydroisoquinolin-1(2H)-one