methyl 6-(methyloxy)-3-phenyl-2-(1,3-thiazol-2-yl)-5-quinoxalinecarboxylate

Base Information

Chemical Name:methyl 6-(methyloxy)-3-phenyl-2-(1,3-thiazol-2-yl)-5-quinoxalinecarboxylate
CAS No.:1160685-37-9
Molecular Formula:C₂₀H₁₅N₃O₃S
Molecular Weight:377.423
Hs Code.:

Synonyms:methyl 6-(methyloxy)-3-phenyl-2-(1,3-thiazol-2-yl)-5-quinoxalinecarboxylate

Suppliers and Price of methyl 6-(methyloxy)-3-phenyl-2-(1,3-thiazol-2-yl)-5-quinoxalinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 6-(methyloxy)-3-phenyl-2-(1,3-thiazol-2-yl)-5-quinoxalinecarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 6-(methyloxy)-3-phenyl-2-(1,3-thiazol-2-yl)-5-quinoxalinecarboxylate

There total 6 articles about methyl 6-(methyloxy)-3-phenyl-2-(1,3-thiazol-2-yl)-5-quinoxalinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.3%

: 1160684-98-9
methyl 2-chloro-6-(methyloxy)-3-phenyl-5-quinoxalinecarboxylate

: 121359-48-6
2-(tri-n-butylstannyl)thiazole

: 1160685-37-9
methyl 6-(methyloxy)-3-phenyl-2-(1,3-thiazol-2-yl)-5-quinoxalinecarboxylate

Guidance literature:: tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; at 150 ℃; for 0.333333h; Microwave irradiation;

Reference yield:

: 13671-00-6
methyl 2,6-difluorobenzoate

: 1160685-37-9
methyl 6-(methyloxy)-3-phenyl-2-(1,3-thiazol-2-yl)-5-quinoxalinecarboxylate

Guidance literature:: Multi-step reaction with 6 steps

1.1: sulfuric acid; nitric acid / 0 - 20 °C

2.1: ammonium hydroxide / ethanol; water / 20 °C

3.1: sodium hydride / mineral oil / 1 h / 0 - 20 °C

4.1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 2585.81 Torr

4.2: 20 °C

5.1: trichlorophosphate / 4 h / Reflux

6.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane / 0.33 h / 150 °C / Microwave irradiation

With ammonium hydroxide; sulfuric acid; hydrogen; nitric acid; sodium hydride; trichlorophosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium 10% on activated carbon; In 1,4-dioxane; ethanol; water; ethyl acetate; mineral oil;

Reference yield:

: 346691-23-4
methyl 2-amino-6-fluoro-3-nitrobenzoate

: 1160685-37-9
methyl 6-(methyloxy)-3-phenyl-2-(1,3-thiazol-2-yl)-5-quinoxalinecarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydride / mineral oil / 1 h / 0 - 20 °C

2.1: hydrogen / palladium 10% on activated carbon / ethyl acetate / 2585.81 Torr

2.2: 20 °C

3.1: trichlorophosphate / 4 h / Reflux

4.1: tetrakis(triphenylphosphine) palladium⁽⁰⁾ / 1,4-dioxane / 0.33 h / 150 °C / Microwave irradiation

With hydrogen; sodium hydride; trichlorophosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; palladium 10% on activated carbon; In 1,4-dioxane; ethyl acetate; mineral oil;