(S)-2-Benzyloxycarbonylamino-6-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid methyl ester

Base Information

• Chemical Name: (S)-2-Benzyloxycarbonylamino-6-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid methyl ester
• CAS No.: 384816-98-2
• Molecular Formula: C₂₂H₂₆N₂O₄
• Molecular Weight: 382.459
• Mol file: 384816-98-2.mol

Synonyms:(S)-2-Benzyloxycarbonylamino-6-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid methyl ester

Chemical Property of (S)-2-Benzyloxycarbonylamino-6-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-2-Benzyloxycarbonylamino-6-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid methyl ester

There total 1 articles about (S)-2-Benzyloxycarbonylamino-6-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

benzaldehyde (100-52-7) + N-(benzyloxycarbonyl)lysine methyl ester hydrochloride (26348-68-5) → (S)-2-Benzyloxycarbonylamino-6-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid methyl ester (384816-98-2)

Guidance literature:

With potassium hydroxide; molecular sieve; In methanol; at 20 ℃; for 15h;

DOI:10.1021/jo010965g

Reference yield: 64.0%

(S)-2-Benzyloxycarbonylamino-6-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid methyl ester (384816-98-2) → C22H26N2O5

Guidance literature:

(S)-2-Benzyloxycarbonylamino-6-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid methyl ester; With iPrCHO-Co(II); oxygen; isobutyraldehyde; In dichloromethane; at 0 ℃; for 1.5h;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h; Further stages.;

DOI:10.1021/jo010965g

Reference yield: 17.0%

pivalaldehyde (630-19-3) + (S)-2-Benzyloxycarbonylamino-6-{[1-phenyl-meth-(E)-ylidene]-amino}-hexanoic acid methyl ester (384816-98-2) → 2-benzyloxycarbonylamino-6-(3-tert-butyl-oxaziridin-2-yl)-hexanoic acid methyl ester + (S)-2-Benzyloxycarbonylamino-6-(3-phenyl-oxaziridin-2-yl)-hexanoic acid methyl ester

Guidance literature:

With water; oxygen; CoCl₂;

DOI:10.1021/jo010965g

upstream raw materials:

benzaldehyde

N-(benzyloxycarbonyl)lysine methyl ester hydrochloride