methyl 4-[hydroxyl(5-{hydroxyl[4-(methoxycarbonyl)phenyl]methyl}furan-2-yl)methyl]benzoate

Base Information

• Chemical Name: methyl 4-[hydroxyl(5-{hydroxyl[4-(methoxycarbonyl)phenyl]methyl}furan-2-yl)methyl]benzoate
• CAS No.: 1312997-06-0
• Molecular Formula: C₂₂H₂₀O₇
• Molecular Weight: 396.397
• Mol file: 1312997-06-0.mol

Synonyms:methyl 4-[hydroxyl(5-{hydroxyl[4-(methoxycarbonyl)phenyl]methyl}furan-2-yl)methyl]benzoate

Chemical Property of methyl 4-[hydroxyl(5-{hydroxyl[4-(methoxycarbonyl)phenyl]methyl}furan-2-yl)methyl]benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 4-[hydroxyl(5-{hydroxyl[4-(methoxycarbonyl)phenyl]methyl}furan-2-yl)methyl]benzoate

There total 1 articles about methyl 4-[hydroxyl(5-{hydroxyl[4-(methoxycarbonyl)phenyl]methyl}furan-2-yl)methyl]benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

furan (110-00-9) + methyl 4-formylbenzoate (1571-08-0) → methyl 4-[hydroxyl(5-{hydroxyl[4-(methoxycarbonyl)phenyl]methyl}furan-2-yl)methyl]benzoate (1312997-06-0)

Guidance literature:

furan; With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In hexane; at 20 ℃; for 1h; Inert atmosphere;

methyl 4-formylbenzoate; In tetrahydrofuran; hexane; for 0.25h; Inert atmosphere; Cooling with ice;

With water; ammonium chloride; In tetrahydrofuran; hexane; Inert atmosphere; Cooling with ice;

DOI:10.1016/j.tet.2011.04.034

Reference yield: 58.0%

pyrrole (109-97-7,30604-81-0) + methyl 4-[hydroxyl(5-{hydroxyl[4-(methoxycarbonyl)phenyl]methyl}furan-2-yl)methyl]benzoate (1312997-06-0) → C30H26N2O5

Guidance literature:

With boron trifluoride diethyl etherate; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1002/chem.201405856

Reference yield: 14.0%

pyrrole (109-97-7,30604-81-0) + 3,5-Di-tert-butylbenzaldehyde (17610-00-3) + methyl 4-[hydroxyl(5-{hydroxyl[4-(methoxycarbonyl)phenyl]methyl}furan-2-yl)methyl]benzoate (1312997-06-0) → C64H65N3O5 + 5,10,15,20-tetrakis-(3,5-di-tert-butylphenyl)porphyrin (89372-90-7)

Guidance literature:

pyrrole; 3,5-Di-tert-butylbenzaldehyde; methyl 4-[hydroxyl(5-{hydroxyl[4-(methoxycarbonyl)phenyl]methyl}furan-2-yl)methyl]benzoate; With boron trifluoride diethyl etherate; In dichloromethane; at 20 ℃; for 1h; Inert atmosphere;

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; for 1h;

DOI:10.1016/j.tet.2011.04.034

upstream raw materials:

furan

methyl 4-formylbenzoate

Downstream raw materials:

5,10,15,20-tetrakis-(3,5-di-tert-butylphenyl)porphyrin

5,10,15,20-tetra(p-tolyl)porphyrin

5,10,15,20-tetrakis(4-methoxycarbonylphenyl)porphyrin