1-(Methoxymethyl)benzoimidazole

Base Information

• Chemical Name: 1-(Methoxymethyl)benzoimidazole
• CAS No.: 18249-98-4
• Molecular Formula: C9H10 N2 O
• Molecular Weight: 162.19
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID60364236
• Nikkaji Number: J2.802.964K
• Wikidata: Q82148084
• Mol file: 18249-98-4.mol

Synonyms:1-(methoxymethyl)benzoimidazole;18249-98-4;1-(Methoxymethyl)-1H-benzo[d]imidazole;1-(methoxymethyl)benzimidazole;1H-Benzimidazole,1-(methoxymethyl)-(9CI);1-methoxymethylbenzimidazole;SCHEMBL2640498;DTXSID60364236;HMS1789L19;1-(Methoxymethyl)-1H-benzoimidazole;MFCD00956939;AKOS001372429;1-(methoxymethyl)-1H-1,3-benzodiazole;BS-21805;CS-0448691;A880886

Chemical Property of 1-(Methoxymethyl)benzoimidazole

Chemical Property:

• PSA: 27.05000
• LogP: 1.64020
• Storage Temp.: Room temperature.
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 162.079312947
• Heavy Atom Count: 12
• Complexity: 152

Purity/Quality:

97% ^*data from raw suppliers

1-(Methoxymethyl)-1H-benzo[D]imidazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCN1C=NC2=CC=CC=C21

Technology Process of 1-(Methoxymethyl)benzoimidazole

There total 5 articles about 1-(Methoxymethyl)benzoimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

methanol (67-56-1) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + 1,2-diamino-benzene (95-54-5) → 1-(methoxymethyl)-1H-benzo[d]imidazole (18249-98-4)

Guidance literature:

With indium(III) oxide; at 60 ℃; for 2h; Sealed tube;

DOI:10.1016/j.tetlet.2020.152177

Reference yield: 64.2%

methanol (67-56-1) + N1,N2-bis((1H-benzotriazol-1-yl)methyl)-benzene-1,2-diamine (1206484-89-0) → 1-Methylbenzimidazole (1632-83-3) + 1-(methoxymethyl)-1H-benzo[d]imidazole (18249-98-4)

Guidance literature:

With oxygen; for 36h; Reflux;

DOI:10.1016/j.tetlet.2009.10.094

Reference yield: 48.5%

methanol (67-56-1) + carbon disulfide (75-15-0,12122-00-8) + 16H,13H-5:12,7:14-dimethanedibenzo[d,i]-[1,3,6,8]tetraazecine (220-52-0) → 1,3-bis(methoxymethyl)-1,3-dihydro-2H-benzimidazole-2-thione + 1-(methoxymethyl)-1H-benzo[d]imidazole (18249-98-4)

Guidance literature:

at 20 ℃; for 24h; regioselective reaction; Darkness;

DOI:10.3390/molecules17078578

upstream raw materials:

benzoimidazole

chloromethyl methyl ether

methanol

N₁,N₂-bis((1H-benzotriazol-1-yl)methyl)-benzene-1,2-diamine

Downstream raw materials:

<(1H-benzimidazol-2-yl)phenylmethyl>amine

{(S)-1-[(S)-1-((1S,2S)-4-{[(1H-Benzoimidazol-2-yl)-phenyl-methyl]-carbamoyl}-1-benzyl-2-hydroxy-butylcarbamoyl)-ethylcarbamoyl]-ethyl}-carbamic acid tert-butyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 18249-98-4 1H-Benzimidazole,1-(methoxymethyl)-(9CI)

Send

Send

Metric Ton KG G Pound L ML

Send

Send