2-Methoxy-3-buten-1-OL

Base Information

• Chemical Name: 2-Methoxy-3-buten-1-OL
• CAS No.: 18231-00-0
• Molecular Formula: C5H10 O2
• Molecular Weight: 102.133
• Hs Code.: 2909499000
• DSSTox Substance ID: DTXSID50370604
• Nikkaji Number: J1.974.302K
• Mol file: 18231-00-0.mol

Synonyms:2-METHOXY-3-BUTEN-1-OL;2-methoxybut-3-en-1-ol;18231-00-0;2-methoxy-3-butene-1-ol;3-Methoxy-1-butene-4-ol;SCHEMBL706106;ETHYL4-ETHOXYPHENYLACETATE;DTXSID50370604;CWSWWBPJNKCKBO-UHFFFAOYSA-N;AKOS006275184;FT-0691734

Chemical Property of 2-Methoxy-3-buten-1-OL

Chemical Property:

• PSA: 29.46000
• LogP: 0.17970
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 102.068079557
• Heavy Atom Count: 7
• Complexity: 52

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC(CO)C=C

Technology Process of 2-Methoxy-3-buten-1-OL

There total 6 articles about 2-Methoxy-3-buten-1-OL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

epoxybutene (930-22-3,62249-81-4) + methanol (67-56-1) → 2-(R)-2-Methoxybut-3-en-1-ol (18231-00-0)

Guidance literature:

With aluminium(III) triflate; at 100 ℃; for 1h; regioselective reaction;

DOI:10.1039/d1ob00021g

Reference yield: 64.0%

tert-butyl-(2-methoxy-but-3-enyloxy)-dimethyl-silane (882165-96-0) → 2-(R)-2-Methoxybut-3-en-1-ol (18231-00-0)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 4h;

DOI:10.1021/ol060221v

Reference yield:

epoxybutene (930-22-3,62249-81-4) + methanol (67-56-1) → erythrol-1-methyl ether (17687-76-2) + 2-(R)-2-Methoxybut-3-en-1-ol (18231-00-0)

Guidance literature:

With sodium methylate;

DOI:10.1021/ja01183a012

upstream raw materials:

epoxybutene

methanol

sodium methylate

trifluoroborane diethyl ether

Downstream raw materials:

2-methoxy-1,3-butadiene

2-methoxy-1-butanol

2-methoxybut-3-enyl benzoate

α-methoxy-n-butyric acid