Technology Process of 2-iodo-4,6-dihydroxy-5-methylbenzaldehyde
There total 2 articles about 2-iodo-4,6-dihydroxy-5-methylbenzaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
boron tribromide;
In
dichloromethane;
for 18h;
Inert atmosphere;
DOI:10.1021/jo102448n
- Guidance literature:
-
Multi-step reaction with 2 steps
1: n-butyllithium; 1,2-Diiodoethane; N,N',N'-trimethylenediamine / tetrahydrofuran / -40 - 20 °C / Inert atmosphere
2: boron tribromide / dichloromethane / 18 h / Inert atmosphere
With
n-butyllithium; 1,2-Diiodoethane; boron tribromide; N,N',N'-trimethylenediamine;
In
tetrahydrofuran; dichloromethane;
DOI:10.1021/jo102448n
- Guidance literature:
-
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; potassium carbonate; diisopropylamine; tri tert-butylphosphoniumtetrafluoroborate;
In
dichloromethane;
at 20 ℃;
for 13h;
Inert atmosphere;
DOI:10.1021/jo102448n
