Acetamide,N-(2-methyl-4-pyridinyl)-

Base Information

• Chemical Name: Acetamide,N-(2-methyl-4-pyridinyl)-
• CAS No.: 18085-47-7
• Molecular Formula: C₈H₁₀N₂O
• Molecular Weight: 150.18
• Hs Code.: 29333990
• Mol file: 18085-47-7.mol

Synonyms:Acetamide,N-(2-methyl-4-pyridyl)- (8CI)

Chemical Property of Acetamide,N-(2-methyl-4-pyridinyl)-

Chemical Property:

• Refractive Index: 1.572
• PSA: 41.99000
• LogP: 1.42140
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

2-Methyl-4-acetamidopyridine 97% ^*data from reagent suppliers

Safty Information:

• Statements: 20/21/22-36/37/38
• Safety Statements: 16-26-37/39

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Acetamide,N-(2-methyl-4-pyridinyl)-

There total 2 articles about Acetamide,N-(2-methyl-4-pyridinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

3-methyl-4-pyridinamine (18437-58-6) + acetic anhydride (108-24-7) → 4-acetylamino-2-methylpyridine (18085-47-7)

Guidance literature:

With triethylamine; In acetone; for 48h; Heating;

Reference yield:

→ 4-acetylamino-2-methylpyridine (18085-47-7)

Guidance literature:

4-Amino-2-methyl-pyridin, Acetanhydrid; S.1085;

DOI:10.1039/j39680001082

Reference yield:

4-acetylamino-2-methylpyridine (18085-47-7) → 4-acetylaminopyridine-2-carboxylic acid (84487-16-1)

Guidance literature:

With potassium permanganate; at 75 ℃; for 10h;

upstream raw materials:

3-methyl-4-pyridinamine

acetic anhydride

Downstream raw materials:

4-acetylaminopyridine-2-carboxylic acid

4-aminopyridine-2-carboxylic acid

Refernces