Technology Process of C28H34N8O
There total 8 articles about C28H34N8O which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1-(2-amino-1,1-dimethyl-ethyl)-3-(4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamine hydrobromide;
With
sodium carbonate;
In
dichloromethane; water;
at 20 ℃;
for 1h;
C12H16N2O2*ClH;
With
dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 24h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: pyridine; p-toluenesulfonyl chloride / 0 - 20 °C
2.1: caesium carbonate / palladium diacetate; catacxium A / toluene; water / 24 h / 95 °C / Inert atmosphere
3.1: sodium hydroxide; water / methanol / 20 °C
3.2: pH 2
4.1: sodium carbonate / dichloromethane; water / 1 h / 20 °C
4.2: 24 h / 20 °C
With
pyridine; water; sodium carbonate; caesium carbonate; p-toluenesulfonyl chloride; sodium hydroxide;
palladium diacetate; catacxium A;
In
methanol; dichloromethane; water; toluene;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: caesium carbonate / palladium diacetate; catacxium A / toluene; water / 24 h / 95 °C / Inert atmosphere
2.1: sodium hydroxide; water / methanol / 20 °C
2.2: pH 2
3.1: sodium carbonate / dichloromethane; water / 1 h / 20 °C
3.2: 24 h / 20 °C
With
water; sodium carbonate; caesium carbonate; sodium hydroxide;
palladium diacetate; catacxium A;
In
methanol; dichloromethane; water; toluene;
