di-tert-butyl (5-tert-butyl-2-methoxyphenyl)-1,3-dicarbamate

Base Information

• Chemical Name: di-tert-butyl (5-tert-butyl-2-methoxyphenyl)-1,3-dicarbamate
• CAS No.: 854669-30-0
• Molecular Formula: C₂₁H₃₄N₂O₅
• Molecular Weight: 394.511
• Mol file: 854669-30-0.mol

Synonyms:di-tert-butyl (5-tert-butyl-2-methoxyphenyl)-1,3-dicarbamate

Chemical Property of di-tert-butyl (5-tert-butyl-2-methoxyphenyl)-1,3-dicarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of di-tert-butyl (5-tert-butyl-2-methoxyphenyl)-1,3-dicarbamate

There total 1 articles about di-tert-butyl (5-tert-butyl-2-methoxyphenyl)-1,3-dicarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

5-tert-butyl-2-methoxybenzene-1,3-diamine (473269-70-4) + di-tert-butyl dicarbonate (24424-99-5) → tert-butyl (3-amino-5-tert-butyl-2-methoxyphenyl)carbamate + di-tert-butyl (5-tert-butyl-2-methoxyphenyl)-1,3-dicarbamate (854669-30-0)

Guidance literature:

In tert-butyl alcohol; at 20 ℃; for 3h;

DOI:10.1021/ol050493i

Reference yield:

di-tert-butyl (5-tert-butyl-2-methoxyphenyl)-1,3-dicarbamate (854669-30-0) + methyl iodide (74-88-4) → [3-(tert-butoxycarbonyl-methyl-amino)-5-tert-butyl-2-methoxy-phenyl]-methyl-carbamic acid tert-butyl ester

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃;

DOI:10.1021/ol050493i

Reference yield:

di-tert-butyl (5-tert-butyl-2-methoxyphenyl)-1,3-dicarbamate (854669-30-0) + benzyl bromide (100-39-0) → benzyl-[3-(benzyl-tert-butoxycarbonyl-amino)-5-tert-butyl-2-methoxy-phenyl]-carbamic acid tert-butyl ester

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 0 - 20 ℃;

DOI:10.1021/ol062459p

upstream raw materials:

5-tert-butyl-2-methoxybenzene-1,3-diamine

di-tert-butyl dicarbonate