C₄₃H₅₉N₅O₇S₂

Base Information

• Chemical Name: C₄₃H₅₉N₅O₇S₂
• CAS No.: 1307901-07-0
• Molecular Formula: C₄₃H₅₉N₅O₇S₂
• Molecular Weight: 822.103
• Mol file: 1307901-07-0.mol

Synonyms:C₄₃H₅₉N₅O₇S₂

Chemical Property of C₄₃H₅₉N₅O₇S₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₄₃H₅₉N₅O₇S₂

There total 5 articles about C₄₃H₅₉N₅O₇S₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(2S)-N-[5-methoxy-4-(2-propynyloxy)-2-nitrobenzoyl]-pyrrolidine-2-carboxaldehyde diethyl-dithioacetal (1037070-06-6) + 3-(5-azidopentyloxy)-17-hydroxy-1,3,5(10)-estratriene (1307900-64-6) → C43H59N5O7S2 (1307901-07-0)

Guidance literature:

With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; tert-butyl alcohol; at 20 ℃; for 12h;

DOI:10.1016/j.bmc.2011.03.015

Reference yield:

1,5-dibromo-pentane (111-24-0) → C43H59N5O7S2 (1307901-07-0)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium carbonate / N,N-dimethyl-formamide / 10 h / 20 °C

2: sodium azide / N,N-dimethyl-formamide / 60 - 70 °C

3: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; tert-butyl alcohol / 12 h / 20 °C

With sodium azide; copper(ll) sulfate pentahydrate; potassium carbonate; sodium L-ascorbate; In water; N,N-dimethyl-formamide; tert-butyl alcohol;

DOI:10.1016/j.bmc.2011.03.015

Reference yield:

3-(5-bromopentoxy)-estra-1,3,5(10)-triene-17β-ol (22034-75-9) → C43H59N5O7S2 (1307901-07-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide / N,N-dimethyl-formamide / 60 - 70 °C

2: copper(ll) sulfate pentahydrate; sodium L-ascorbate / water; tert-butyl alcohol / 12 h / 20 °C

With sodium azide; copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; N,N-dimethyl-formamide; tert-butyl alcohol;

DOI:10.1016/j.bmc.2011.03.015

upstream raw materials:

(2S)-N-[5-methoxy-4-(2-propynyloxy)-2-nitrobenzoyl]-pyrrolidine-2-carboxaldehyde diethyl-dithioacetal

3-(5-azidopentyloxy)-17-hydroxy-1,3,5⁽¹⁰⁾-estratriene

1,5-dibromo-pentane

3-(5-bromopentoxy)-estra-1,3,5(10)-triene-17β-ol