N-[(2-pyridyl)methylidene]-2-hydroxy-5-chlorophenylamine

Base Information

• Chemical Name: N-[(2-pyridyl)methylidene]-2-hydroxy-5-chlorophenylamine
• CAS No.: 20211-18-1
• Molecular Formula: C₁₂H₉ClN₂O
• Molecular Weight: 232.669
• Mol file: 20211-18-1.mol

Synonyms:N-[(2-pyridyl)methylidene]-2-hydroxy-5-chlorophenylamine

Chemical Property of N-[(2-pyridyl)methylidene]-2-hydroxy-5-chlorophenylamine

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of N-[(2-pyridyl)methylidene]-2-hydroxy-5-chlorophenylamine

There total 1 articles about N-[(2-pyridyl)methylidene]-2-hydroxy-5-chlorophenylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

pyridine-2-carbaldehyde (1121-60-4) + 2-hydroxy-5-chloro-aniline (95-85-2) → N-[(2-pyridyl)methylidene]-2-hydroxy-5-chlorophenylamine (20211-18-1)

Guidance literature:

In ethanol; for 2h; Heating;

DOI:10.1039/DT9940003553

Reference yield: 88.0%

ammonium hexafluorophosphate + N-[(2-pyridyl)methylidene]-2-hydroxy-5-chlorophenylamine (20211-18-1) + nickel dichloride (83864-14-6) → [Ni(2-(2-(C5H4N)CH=N)-4-ClC6H3O)2]

Guidance literature:

With Et₃N; In ethanol; N2-atmosphere; treatment of NiCl2 with two-fold excess of Schiff base inpresence of Et3N, then addn. of excess NH4PF6; elem. anal.;

DOI:10.1039/DT9940003553

upstream raw materials:

pyridine-2-carbaldehyde

2-hydroxy-5-chloro-aniline