Phenyl Trimethylsilylmethyl Sulfone

Base Information

• Chemical Name: Phenyl Trimethylsilylmethyl Sulfone
• CAS No.: 17872-92-3
• Molecular Formula: C10H16 O2 S Si
• Molecular Weight: 228.387
• Hs Code.: 2931900090
• European Community (EC) Number: 679-678-0
• DSSTox Substance ID: DTXSID10391113
• Nikkaji Number: J364.473A
• Wikidata: Q82188355
• Mol file: 17872-92-3.mol

Synonyms:Phenyl Trimethylsilylmethyl Sulfone;17872-92-3;benzenesulfonylmethyl(trimethyl)silane;(Phenylsulfonylmethyl)trimethylsilane;Benzene, [[(trimethylsilyl)methyl]sulfonyl]-;SCHEMBL3295258;DTXSID10391113;(phenylsulfonyl)trimethylsilylmethane;Phenyl(trimethylsilylmethyl) sulfone;trimethyl(phenylsulfonylmethyl)silane;MFCD00012364;AKOS015840058;[(benzenesulfonyl)methyl]trimethylsilane;AS-66202;4-isopropyl-2-methyl-4,5-dihydrothiazole;FT-0637617;T71947;J-011396

Chemical Property of Phenyl Trimethylsilylmethyl Sulfone

Chemical Property:

• Vapor Pressure: 6.53E-07mmHg at 25°C
• Melting Point: 28-32 °C
• Refractive Index: n20/D 1.493(lit.)
• Boiling Point: 154-156 °C(lit.)
• Flash Point: 48 °F
• PSA: 42.52000
• Density: 1.138 g/mL at 25 °C(lit.)
• LogP: 3.83680
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 228.06402746
• Heavy Atom Count: 14
• Complexity: 266

Purity/Quality:

98%,99%, ^*data from raw suppliers

Phenyl Trimethylsilylmethyl Sulfone >95.0%(GC) ^*data from reagent suppliers

Safty Information:

• Hazard Codes: F,Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)CS(=O)(=O)C1=CC=CC=C1

Technology Process of Phenyl Trimethylsilylmethyl Sulfone

There total 7 articles about Phenyl Trimethylsilylmethyl Sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(phenylsulfanylmethyl)trimethylsilane (17873-08-4) → (phenylsulfonylmethyl)trimethylsilane (17872-92-3)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at -23 ℃;

DOI:10.1039/P19860000195

Reference yield: 95.0%

Phenyl trimethylsilylmethyl sulfoxide (18789-72-5) → (phenylsulfonylmethyl)trimethylsilane (17872-92-3)

Guidance literature:

With n-C₄F₉; perfluoro-cis-2,3-dialkyloxaziridine; n-C₃F₇; In chloroform; trichlorofluoromethane; at -20 ℃; for 0.25h;

DOI:10.1021/jo00089a020

Reference yield: 90.0%

chloro-trimethyl-silane (75-77-4) + methylphenylsulfonate (3112-85-4) → (phenylsulfonylmethyl)trimethylsilane (17872-92-3)

Guidance literature:

With n-butyllithium; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; hexane; 1.) -78 deg C, 5 min; 2.) -40 deg C, 2 h; 3.) up to RT, 24 h;

DOI:10.1016/0022-328X(85)87362-9

upstream raw materials:

(phenylsulfanylmethyl)trimethylsilane

Phenyl trimethylsilylmethyl sulfoxide

chloro-trimethyl-silane

methylphenylsulfonate

Downstream raw materials:

cycloprop-1-enyl phenyl sulphone

(ZE,E)-3-dimethylpent-1,3-dienyl phenyl sulphone

4-phenylsulphonyl-3-methylbut-2-enal

4,4-dimethoxy-2-methylbut-1-enyl phenyl sulphone

Refernces

• 1、 DesMarteau, Darryl D.,Petrov, Viacheslav A.,Montanari, Vittorio,Pregnolato, Massimo,Resnati, Giuseppe. "Mild and Selective Oxygenation of Sulfides to Sulfoxides and Sulfones by Perfluoro-cis-2,3-dialkyloxaziridines". . p. 2762 - 2765. Retrieved 2007/10/02.
• 2、 Ager, David J.. "The Synthesis of Ketones via α-Silyl Sulphides". . p. 195 - 204. Retrieved 2007/10/02.