2-[4-(Aminomethyl)phenyl]propan-2-ol

Base Information

Chemical Name:2-[4-(Aminomethyl)phenyl]propan-2-ol
CAS No.:214758-90-4
Molecular Formula:C₁₀H₁₅NO
Molecular Weight:165.235
Hs Code.:
European Community (EC) Number:832-350-2
Nikkaji Number:J2.359.168E

Synonyms:2-[4-(aminomethyl)phenyl]propan-2-ol;214758-90-4;2-(4-(aminomethyl)phenyl)propan-2-ol;SCHEMBL4825874;JXABOQLRHAMRAQ-UHFFFAOYSA-N;AKOS006307564;2-(4-aminomethyl-phenyl)-propan-2-ol;NS-01324;4-(1-Hydroxy-1-methyl-ethyl)-benzyl amine;CS-0375514;D86357;EN300-142434;1-(Aminomethyl)-4-(1-hydroxy-1-methylethyl)benzene;Z1198305621

Suppliers and Price of 2-[4-(Aminomethyl)phenyl]propan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 1 raw suppliers

Chemical Property of 2-[4-(Aminomethyl)phenyl]propan-2-ol

Chemical Property:

XLogP3:0.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:165.115364102
Heavy Atom Count:12
Complexity:137

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C1=CC=C(C=C1)CN)O

Technology Process of 2-[4-(Aminomethyl)phenyl]propan-2-ol

There total 6 articles about 2-[4-(Aminomethyl)phenyl]propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 77802-22-3
4-(2-hydroxypropan-2-yl)benzenecarbonitrile

: 214758-90-4
4-(1-hydroxy-1-methyl-ethyl)benzyl amine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 0 - 20 ℃; for 0.333333h; Reflux;

Reference yield:

: 3058-39-7
4-iodobenzonitrile

: 214758-90-4
4-(1-hydroxy-1-methyl-ethyl)benzyl amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 - -70 °C

1.2: 16 h / -70 - 20 °C

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 °C / Reflux

With lithium aluminium tetrahydride; n-butyllithium; In tetrahydrofuran; hexane;

Reference yield:

: 13816-33-6
p-Cyanocumen

: 214758-90-4
4-(1-hydroxy-1-methyl-ethyl)benzyl amine

Guidance literature:: Multi-step reaction with 2 steps

1: 67 percent / potassium permanganate; sodium carbonate / H₂O; 2-methyl-propan-2-ol / 40 °C

2: 82 percent / lithium aluminum hydride / tetrahydrofuran / 2 h / Heating

With potassium permanganate; lithium aluminium tetrahydride; sodium carbonate; In tetrahydrofuran; water; tert-butyl alcohol;
DOI:10.1080/00397910600636733