1-Benzylpiperidine-2-thione

Base Information

Chemical Name:1-Benzylpiperidine-2-thione
CAS No.:17642-89-6
Molecular Formula:C12H15 N S
Molecular Weight:205.324
Hs Code.:
DSSTox Substance ID:DTXSID001293608
Nikkaji Number:J699.022C
Mol file:17642-89-6.mol

Synonyms:1-Benzylpiperidine-2-thione;17642-89-6;2-Piperidinethione, 1-(phenylmethyl)-;2-Piperidinethione, 1-(phenylmethyl)-;1-benzyl-2-piperidinethione;1-benzyl-piperidine-2-thione;SCHEMBL11490206;DTXSID001293608;1-(Phenylmethyl)-2-piperidinethione;2-Piperidinethione,1-(phenylmethyl)-;AKOS015905064

Suppliers and Price of 1-Benzylpiperidine-2-thione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-Benzylpiperidine-2-thione

Chemical Property:

PSA：35.33000
LogP:2.93780
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:205.09252066
Heavy Atom Count:14
Complexity:197

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(C(=S)C1)CC2=CC=CC=C2

Technology Process of 1-Benzylpiperidine-2-thione

There total 4 articles about 1-Benzylpiperidine-2-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 4783-65-7
N-benzyl-2-piperidinone

: 17642-89-6
1-benzylpiperidine-2-thione

Guidance literature:: With Lawessons reagent; In dichloromethane; at 20 ℃;
DOI:10.1021/acs.joc.7b02150

Reference yield:

: 675-20-7
piperidin-2-one

: 17642-89-6
1-benzylpiperidine-2-thione

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran / Inert atmosphere

2: Lawessons reagent / dichloromethane / 20 °C / Inert atmosphere

With Lawessons reagent; sodium hydride; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.saa.2013.09.108

Reference yield:

: 100-39-0
benzyl bromide

: 17642-89-6
1-benzylpiperidine-2-thione

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran / Inert atmosphere

2: Lawessons reagent / dichloromethane / 20 °C / Inert atmosphere

With Lawessons reagent; sodium hydride; In tetrahydrofuran; dichloromethane;
DOI:10.1016/j.saa.2013.09.108