4,7,8-trimethoxy-3-(4-methoxyphenyl)dibenzo[b,d]furan-1,2-diyl diacetate

Base Information

Chemical Name:4,7,8-trimethoxy-3-(4-methoxyphenyl)dibenzo[b,d]furan-1,2-diyl diacetate
CAS No.:1541073-10-2
Molecular Formula:C₂₆H₂₄O₉
Molecular Weight:480.471
Hs Code.:

Synonyms:4,7,8-trimethoxy-3-(4-methoxyphenyl)dibenzo[b,d]furan-1,2-diyl diacetate

Suppliers and Price of 4,7,8-trimethoxy-3-(4-methoxyphenyl)dibenzo[b,d]furan-1,2-diyl diacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4,7,8-trimethoxy-3-(4-methoxyphenyl)dibenzo[b,d]furan-1,2-diyl diacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4,7,8-trimethoxy-3-(4-methoxyphenyl)dibenzo[b,d]furan-1,2-diyl diacetate

There total 19 articles about 4,7,8-trimethoxy-3-(4-methoxyphenyl)dibenzo[b,d]furan-1,2-diyl diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 146905-24-0
4,7,8-trihydroxy-3-(4-hydroxyphenyl)dibenzo[b,d]furan-1,2-diyl diacetate

: 74-88-4
methyl iodide

: 1541073-10-2
4,7,8-trimethoxy-3-(4-methoxyphenyl)dibenzo[b,d]furan-1,2-diyl diacetate

: 1541073-13-5
3-(4-hydroxyphenyl)-4,7,8-trimethoxydibenzo[b,d]furan-1,2-diyl diacetate

Guidance literature:: With potassium carbonate; In acetone; for 16h; regioselective reaction; Reflux;
DOI:10.1021/jo402492d

Reference yield: 46.0%

: 4-formyl-7,8-dimethoxy-3-(4-methoxyphenyl)dibenzo[b,d]furan-1,2-diyl diacetate

: 74-88-4
methyl iodide

: 1541073-10-2
4,7,8-trimethoxy-3-(4-methoxyphenyl)dibenzo[b,d]furan-1,2-diyl diacetate

Guidance literature:: 4-formyl-7,8-dimethoxy-3-(4-methoxyphenyl)dibenzo[b,d]furan-1,2-diyl diacetate; With sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 20 ℃; Inert atmosphere;

With potassium carbonate; In ethanol; dichloromethane; at 20 ℃; for 6h; Inert atmosphere;

methyl iodide; With potassium carbonate; In acetone; at 20 ℃; for 17h; Inert atmosphere;
DOI:10.1021/acs.joc.8b00792

Reference yield:

: 1541073-33-9
8,9-dimethoxy-5-(methoxymethoxy)-4-(4-methoxyphenyl)-benzo[b][1,3]dioxolo[4,5-e]benzofuran

: 1541073-10-2
4,7,8-trimethoxy-3-(4-methoxyphenyl)dibenzo[b,d]furan-1,2-diyl diacetate

Guidance literature:: Multi-step reaction with 6 steps

1.1: hydrogenchloride / tetrahydrofuran; 1,4-dioxane / 2 h / 20 °C

2.1: pyridine / dichloromethane / 0.5 h / 0 °C

3.1: toluene / 2 h / Reflux

4.1: acetic acid / 0.5 h / 20 °C

5.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.5 h / -78 °C

5.2: -78 - 20 °C

5.3: 16 h

6.1: potassium carbonate / acetone / 16 h / Reflux

With pyridine; hydrogenchloride; potassium carbonate; acetic acid; lithium hexamethyldisilazane; In tetrahydrofuran; 1,4-dioxane; dichloromethane; acetone; toluene;
DOI:10.1021/jo402492d