1-(2-Methoxy-4-methylphenyl)propan-2-amine

Base Information

Chemical Name:1-(2-Methoxy-4-methylphenyl)propan-2-amine
CAS No.:52336-48-8
Molecular Formula:C₁₁H₁₇NO
Molecular Weight:179.262
Hs Code.:
DSSTox Substance ID:DTXSID401279870
Nikkaji Number:J456.890G
ChEMBL ID:CHEMBL166040

Synonyms:CHEMBL166040;1-(2-methoxy-4-methylphenyl)propan-2-amine;52336-48-8;DTXSID401279870;BDBM50005259;AKOS006290448;2-Methoxy-alpha,4-dimethylbenzeneethanamine;1-Methyl-2-(2-methoxy-4-methylphenyl)ethanamine;2-(2-Methoxy-4-methyl-phenyl)-1-methyl-ethylamine

Suppliers and Price of 1-(2-Methoxy-4-methylphenyl)propan-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(2-Methoxy-4-methylphenyl)propan-2-amine

Chemical Property:

XLogP3:2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:179.131014166
Heavy Atom Count:13
Complexity:149

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=CC(=C(C=C1)CC(C)N)OC

Technology Process of 1-(2-Methoxy-4-methylphenyl)propan-2-amine

There total 5 articles about 1-(2-Methoxy-4-methylphenyl)propan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 139102-35-5
1-(2-methoxy-4-methylphenyl)-2-nitropropene

: 52336-48-8
(+/-)-1-(2-methoxy-4-methylphenyl)-2-aminopropane

Guidance literature:: With lithium aluminium tetrahydride;
DOI:10.1021/jm00256a016

Reference yield:

: 10542-80-0
(2-methoxy-4-methylphenyl)methanol

: 52336-48-8
(+/-)-1-(2-methoxy-4-methylphenyl)-2-aminopropane

Guidance literature:: Multi-step reaction with 3 steps

1: 59 percent / pyridinium dichromate / CH₂Cl₂ / 51 h / Ambient temperature

2: 91 percent / ammonium acetate / 1.) reflux, 8 h, 2.) RT, 60 h

3: LiAlH₄ / diethyl ether / 1.) reflux, 6 h, 2.) RT, 16 h

With ammonium acetate; lithium aluminium tetrahydride; dipyridinium dichromate; In diethyl ether; dichloromethane;
DOI:10.1021/jm00082a014

Reference yield:

: 57415-35-7
2-methoxy-4-methylbenzaldehyde

: 52336-48-8
(+/-)-1-(2-methoxy-4-methylphenyl)-2-aminopropane

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / ammonium acetate / 1.) reflux, 8 h, 2.) RT, 60 h

2: LiAlH₄ / diethyl ether / 1.) reflux, 6 h, 2.) RT, 16 h

With ammonium acetate; lithium aluminium tetrahydride; In diethyl ether;
DOI:10.1021/jm00082a014