Ethyl 5-aminopyridine-3-carboxylate

Base Information

Chemical Name:Ethyl 5-aminopyridine-3-carboxylate
CAS No.:17285-76-6
Molecular Formula:C8H10 N2 O2
Molecular Weight:166.18
Hs Code.:29333990
DSSTox Substance ID:DTXSID50358705
Wikidata:Q82139482
Mol file:17285-76-6.mol

Synonyms:17285-76-6;ethyl 5-aminopyridine-3-carboxylate;5-Amino-3-pyridinecarboxylic acid ethyl ester;ethyl 5-aminonicotinate;Ethyl 5-amino-3-pyridinecarboxylate;5-Amino-nicotinic acid ethyl ester;Oprea1_820025;SCHEMBL3664506;DTXSID50358705;VKVSFDPQJVUTAM-UHFFFAOYSA-N;AB3715;MFCD01087129;STK524487;AKOS004911034;AS-5508;SB54342;5-Amino-3-pyridinecarboxylicacidethylester;CS-0298920;FT-0714243;EN300-1254431

Suppliers and Price of Ethyl 5-aminopyridine-3-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acints
5-Amino-nicotinicacidethylester 95%+
1g
$ 79.75

Acints
5-Amino-nicotinicacidethylester 95%+
5g
$ 326.25

Advanced Chemicals Intermediatesced Chemicals Intermediates
5-Amino-nicotinicacidethylester 95%+
1g
$ 79.75

AK Scientific
Ethyl5-amino-3-pyridinecarboxylate
1g
$ 506.00

American Custom Chemicals Corporation
ETHYL 5-AMINOPYRIDINE-3-CARBOXYLATE 95.00%
1G
$ 972.51

American Custom Chemicals Corporation
ETHYL 5-AMINOPYRIDINE-3-CARBOXYLATE 95.00%
5G
$ 2193.35

Crysdot
Ethyl5-amino-3-pyridinecarboxylate 95+%
5g
$ 345.00

Frontier Specialty Chemicals
5-Amino-3-pyridinecarboxylicacidethylester 97%
5g
$ 458.00

Frontier Specialty Chemicals
5-Amino-3-pyridinecarboxylicacidethylester 97%
1g
$ 108.00

Matrix Scientific
5-Amino-nicotinic acid ethyl ester 95+%
1g
$ 338.00

Total 15 raw suppliers

Chemical Property of Ethyl 5-aminopyridine-3-carboxylate

Chemical Property:

Vapor Pressure:0.000193mmHg at 25°C
Melting Point:95-97 °C
Refractive Index:1.558
Boiling Point:328.1oC at 760 mmHg
PKA:4.23±0.20(Predicted)
Flash Point:152.2oC
PSA：65.21000
Density:1.192g/cm3
LogP:1.42170
Storage Temp.:2-8°C(protect from light)
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:166.074227566
Heavy Atom Count:12
Complexity:161

Purity/Quality:

98%, ^*data from raw suppliers

5-Amino-nicotinicacidethylester 95%+ ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Statements: 24/25-36/37/38
Safety Statements: 26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC(=CN=C1)N

Technology Process of Ethyl 5-aminopyridine-3-carboxylate

There total 3 articles about Ethyl 5-aminopyridine-3-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 24242-19-1
5-aminonicotinic acid

: 64-17-5
ethanol

: 17285-76-6
5-aminonicotinic acid ethyl ester

Guidance literature:: With thionyl chloride; at 0 ℃; Reflux;

Reference yield:

: 20826-04-4
5-bromo-3-pyridinecarboxylic acid

: 17285-76-6
5-aminonicotinic acid ethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: ammonia / copper(II) sulfate / water / 15 h / 180 °C

2: hydrogenchloride / 1,4-dioxane / 16 h / Heating / reflux

With hydrogenchloride; ammonia; copper(II) sulfate; In 1,4-dioxane; water;