cis-(S-dimethylsulfoxide)(N-morpholino-N'-(benzoyl)thioureato)chloroplatinum(II)

Base Information

• Chemical Name: cis-(S-dimethylsulfoxide)(N-morpholino-N'-(benzoyl)thioureato)chloroplatinum(II)
• CAS No.: 302328-85-4
• Molecular Formula: C₁₄H₁₉ClN₂O₃PtS₂
• Molecular Weight: 557.981
• Mol file: 302328-85-4.mol

Synonyms:cis-(S-dimethylsulfoxide)(N-morpholino-N'-(benzoyl)thioureato)chloroplatinum(II)

Chemical Property of cis-(S-dimethylsulfoxide)(N-morpholino-N'-(benzoyl)thioureato)chloroplatinum(II)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of cis-(S-dimethylsulfoxide)(N-morpholino-N'-(benzoyl)thioureato)chloroplatinum(II)

There total 1 articles about cis-(S-dimethylsulfoxide)(N-morpholino-N'-(benzoyl)thioureato)chloroplatinum(II) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

N-(morpholinothiocarbonyl)benzamide (40398-30-9) + cis-dichlorobis(dimethylsulfoxide)platinum(II) (75992-73-3,25794-47-2,30729-25-0,15274-33-6,22840-91-1,14568-13-9) → cis-(S-dimethylsulfoxide)(N-morpholino-N'-(benzoyl)thioureato)chloroplatinum(II) (302328-85-4) + cis-bis(N-morpholino-N'-(benzoyl)thioureato)platinum(II) (76850-77-6)

Guidance literature:

With sodium acetate; In ethanol; dimethyl sulfoxide; acetonitrile; soln. of thiourea derivative in CH3CN/ethanol added dropwise to soln. ofcis-PtCl2(dmso)2 in CH3CN/DMSO under stirring, aq. soln. of sodium acet ate added, stirred for 48 h; flash column chromy. (silica), concd., H2O added, cooled at 4°C overnight, ppt. filtered off, washed with water and small amt. of ethanol, dried under vac. over silica; elem. anal.;

DOI:10.1016/S0277-5387(00)00419-8

Reference yield:

cis-(S-dimethylsulfoxide)(N-morpholino-N'-(benzoyl)thioureato)chloroplatinum(II) (302328-85-4) + triphenylphosphine (603-35-0) → cis-dichlorobis(triphenylphosphine)platinum(II) (10199-34-5,14056-88-3,15604-36-1) + cis-(P,S)-[PtCl(O(CH2)4NCSNCOC6H5)(PPh3)] (331823-21-3) + [Pt(O(CH2)4NCSNCOC6H5)(PPh3)2](1+) (331823-25-7) + [PtCl(OC4H8NCSNHCOC6H5)(PPh3)2](1+)

Guidance literature:

In chloroform-d1; byproducts: DMSO, Cl(1-), triphenylphosphine oxide; addn. of PPh3 (2 equiv.) to soln. of Pt(OC4H8NCSNCOC6H5)Cl(DMSO) (1 equiv.) in CDCl3 in NMR tube, vigorously shaking; not isolated, detected by NMR; Kinetics;

DOI:10.1039/b007589m

upstream raw materials:

N-(morpholinothiocarbonyl)benzamide

cis-dichlorobis(dimethylsulfoxide)platinum(II)

Downstream raw materials:

cis-dichlorobis(triphenylphosphine)platinum(II)

cis-(P,S)-[PtCl(O(CH₂)4NCSNCOC₆H₅)(PPh₃)]

[Pt(O(CH₂)4NCSNCOC₆H₅)(PPh₃)2]⁽¹⁺⁾