N-benzyl-6-<2-(methylsulfonyloxy)ethyl>-2-(3,4-dimethoxyphenyl)-3,4-dimethoxybenzamide

Base Information

Chemical Name:N-benzyl-6-<2-(methylsulfonyloxy)ethyl>-2-(3,4-dimethoxyphenyl)-3,4-dimethoxybenzamide
CAS No.:85010-28-2
Molecular Formula:C₂₇H₃₁NO₈S
Molecular Weight:529.611
Hs Code.:

Synonyms:N-benzyl-6-<2-(methylsulfonyloxy)ethyl>-2-(3,4-dimethoxyphenyl)-3,4-dimethoxybenzamide

Suppliers and Price of N-benzyl-6-<2-(methylsulfonyloxy)ethyl>-2-(3,4-dimethoxyphenyl)-3,4-dimethoxybenzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-benzyl-6-<2-(methylsulfonyloxy)ethyl>-2-(3,4-dimethoxyphenyl)-3,4-dimethoxybenzamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-benzyl-6-<2-(methylsulfonyloxy)ethyl>-2-(3,4-dimethoxyphenyl)-3,4-dimethoxybenzamide

There total 8 articles about N-benzyl-6-<2-(methylsulfonyloxy)ethyl>-2-(3,4-dimethoxyphenyl)-3,4-dimethoxybenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 124-63-0
methanesulfonyl chloride

: 85031-20-5
N-benzyl-6-(2-hydroxyethyl)-2-(3,4-dimethoxyphenyl)-3,4-dimethoxybenzamide

: 85010-28-2
N-benzyl-6-<2-(methylsulfonyloxy)ethyl>-2-(3,4-dimethoxyphenyl)-3,4-dimethoxybenzamide

Guidance literature:: With pyridine;

Reference yield:

: 573-11-5
2,3,4-Trimethoxy-benzoic acid

: 85010-28-2
N-benzyl-6-<2-(methylsulfonyloxy)ethyl>-2-(3,4-dimethoxyphenyl)-3,4-dimethoxybenzamide

Guidance literature:: Multi-step reaction with 8 steps

1: SOCl₂ / 24 h / Ambient temperature

2: CH₂Cl₂ / 1 h / 0 °C

3: 93 percent / SOCl₂

4: 92 percent / tetrahydrofuran / 1.) reflux, 10 min, 2.) room temperature, 20 h

5: 44 percent / n-BuLi / hexane; tetrahydrofuran / 3 h / -10 - -5 °C

6: 79 percent / 3M HCl / H₂O / 0.33 h / Heating

7: 88 percent / benzylamine / 24 h / 120 - 125 °C

8: 97 percent / pyridine

With pyridine; hydrogenchloride; n-butyllithium; thionyl chloride; benzylamine; In tetrahydrofuran; hexane; dichloromethane; water;

Reference yield:

: 85010-19-1
4,4-dimethyl-2-(2,3,4-trimethoxyphenyl)-4,5-oxazoline

: 85010-28-2
N-benzyl-6-<2-(methylsulfonyloxy)ethyl>-2-(3,4-dimethoxyphenyl)-3,4-dimethoxybenzamide

Guidance literature:: Multi-step reaction with 5 steps

1: 92 percent / tetrahydrofuran / 1.) reflux, 10 min, 2.) room temperature, 20 h

2: 44 percent / n-BuLi / hexane; tetrahydrofuran / 3 h / -10 - -5 °C

3: 79 percent / 3M HCl / H₂O / 0.33 h / Heating

4: 88 percent / benzylamine / 24 h / 120 - 125 °C

5: 97 percent / pyridine

With pyridine; hydrogenchloride; n-butyllithium; benzylamine; In tetrahydrofuran; hexane; water;