ethyl 6-triphenylmethylaminohexanoic acid

Base Information

• Chemical Name: ethyl 6-triphenylmethylaminohexanoic acid
• CAS No.: 228110-68-7
• Molecular Formula: C₂₇H₃₁NO₂
• Molecular Weight: 401.549
• Mol file: 228110-68-7.mol

Synonyms:ethyl 6-triphenylmethylaminohexanoic acid

Chemical Property of ethyl 6-triphenylmethylaminohexanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 6-triphenylmethylaminohexanoic acid

There total 3 articles about ethyl 6-triphenylmethylaminohexanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethyl 6-aminocaproate hydrochloride (3633-17-8) + trityl chloride (76-83-5) → ethyl 6-triphenylmethylaminohexanoic acid (228110-68-7)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1016/S0968-0896(00)00029-8

Reference yield:

6-aminohexanoic acid (60-32-2,93208-38-9) → ethyl 6-triphenylmethylaminohexanoic acid (228110-68-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 95 percent / SOCl₂ / 1 h / 20 °C

2: NEt₃ / CH₂Cl₂ / 3 h / 20 °C

With thionyl chloride; triethylamine; In dichloromethane;

DOI:10.1016/S0223-5234(00)01181-8

Reference yield:

ethyl 6-aminohexanoate (371-34-6) + trityl chloride (76-83-5) → ethyl 6-triphenylmethylaminohexanoic acid (228110-68-7)

Guidance literature:

With triethylamine; for 3h; Yield given; Ambient temperature;

upstream raw materials:

ethyl 6-aminohexanoate

trityl chloride

ethyl 6-aminocaproate hydrochloride

6-aminohexanoic acid

Downstream raw materials:

C₄₄H₄₂N₁₀O₇S₄

C₄₆H₄₇N₁₁O₅S₄

C₅₈H₅₉N₇O₃S₂

2-[(2-{[2-({2-[6-(trityl-amino)-hexanoylamino]-thiazole-4-carbonyl}-amino)-thiazole-4-carbonyl]-amino}-thiazole-4-carbonyl)-amino]-thiazole-4-carboxylic acid