(tert-butoxycarbonyl)(ethoxycarbonyl)(phenyliodinio)methanide

Base Information

• Chemical Name: (tert-butoxycarbonyl)(ethoxycarbonyl)(phenyliodinio)methanide
• CAS No.: 1093350-36-7
• Molecular Formula: C₁₅H₁₉IO₄
• Molecular Weight: 390.218
• Mol file: 1093350-36-7.mol

Synonyms:(tert-butoxycarbonyl)(ethoxycarbonyl)(phenyliodinio)methanide

Chemical Property of (tert-butoxycarbonyl)(ethoxycarbonyl)(phenyliodinio)methanide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (tert-butoxycarbonyl)(ethoxycarbonyl)(phenyliodinio)methanide

There total 1 articles about (tert-butoxycarbonyl)(ethoxycarbonyl)(phenyliodinio)methanide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

tert-Butyl ethyl malonate (32864-38-3) + [bis(acetoxy)iodo]benzene (3240-34-4) → (tert-butoxycarbonyl)(ethoxycarbonyl)(phenyliodinio)methanide (1093350-36-7)

Guidance literature:

tert-Butyl ethyl malonate; With potassium hydroxide; In dichloromethane; at 20 ℃; for 0.0833333h; Inert atmosphere;

[bis(acetoxy)iodo]benzene; In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1021/jo802208q

Reference yield: 40.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + (tert-butoxycarbonyl)(ethoxycarbonyl)(phenyliodinio)methanide (1093350-36-7) → (+/-)-1-tert-butyl 1-ethyl (1S,2R)-2-phenylcyclopropane-1,1-dicarboxylate + (+/-)-1-tert-butyl 1-ethyl (1R,2R)-2-phenylcyclopropane-1,1-dicarboxylate

Guidance literature:

With rhodium(II) acetate dimer; In dichloromethane; at 20 ℃; for 3h; optical yield given as %de; Inert atmosphere;

DOI:10.1021/jo802208q

Reference yield:

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + (tert-butoxycarbonyl)(ethoxycarbonyl)(phenyliodinio)methanide (1093350-36-7) → tert-butyl ethyl (1S,2S)-2-phenylcyclopropane-1,1-dicarboxylate (1198573-65-7) + tert-butyl ethyl (1R,2R)-2-phenylcyclopropane-1,1-dicarboxylate + tert-butyl ethyl 2-phenylcyclopropane-1,1-dicarboxylate

Guidance literature:

With silver hexafluoroantimonate; C₂₅H₃₀N₂O₂; copper(l) chloride; In toluene; at 0 ℃; for 18h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1021/jo902066y

upstream raw materials:

tert-Butyl ethyl malonate

[bis(acetoxy)iodo]benzene

Downstream raw materials:

tert-butyl ethyl (1S,2S)-2-phenylcyclopropane-1,1-dicarboxylate