n-tert-butoxycarbonyl-ε-(3-benzyloxy-1,4-dihydro-2-methyl-4-oxo-1-pyridyl)-L-norleucyl-β-alanine

Base Information

Chemical Name:n-tert-butoxycarbonyl-ε-(3-benzyloxy-1,4-dihydro-2-methyl-4-oxo-1-pyridyl)-L-norleucyl-β-alanine
CAS No.:398460-96-3
Molecular Formula:C₂₇H₃₇N₃O₇
Molecular Weight:515.607
Hs Code.:

Synonyms:n-tert-butoxycarbonyl-ε-(3-benzyloxy-1,4-dihydro-2-methyl-4-oxo-1-pyridyl)-L-norleucyl-β-alanine

Suppliers and Price of n-tert-butoxycarbonyl-ε-(3-benzyloxy-1,4-dihydro-2-methyl-4-oxo-1-pyridyl)-L-norleucyl-β-alanine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of n-tert-butoxycarbonyl-ε-(3-benzyloxy-1,4-dihydro-2-methyl-4-oxo-1-pyridyl)-L-norleucyl-β-alanine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of n-tert-butoxycarbonyl-ε-(3-benzyloxy-1,4-dihydro-2-methyl-4-oxo-1-pyridyl)-L-norleucyl-β-alanine

There total 5 articles about n-tert-butoxycarbonyl-ε-(3-benzyloxy-1,4-dihydro-2-methyl-4-oxo-1-pyridyl)-L-norleucyl-β-alanine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 398460-94-1
N-tert-butoxycarbonyl-ε-(3-benzyloxy-1,4-dihydro-2-methyl-4-oxo-1-pyridyl)-L-norleucyl-β-alanine ethyl ester

: 398460-96-3
n-tert-butoxycarbonyl-ε-(3-benzyloxy-1,4-dihydro-2-methyl-4-oxo-1-pyridyl)-L-norleucyl-β-alanine

Guidance literature:: With sodium hydroxide; In methanol; at 20 ℃; for 2h;
DOI:10.3987/COM-01-9338

Reference yield:

: 61049-69-2
3-O-benzylmaltol

: 398460-96-3
n-tert-butoxycarbonyl-ε-(3-benzyloxy-1,4-dihydro-2-methyl-4-oxo-1-pyridyl)-L-norleucyl-β-alanine

Guidance literature:: Multi-step reaction with 4 steps

1: aq. NaOH / ethanol / 96 h / 20 °C

2: 37 percent / dioxane; H₂O / 56 h / 0 - 20 °C

3: 85 percent / N-methylmorpholine; 1-hydroxybenzotriazole; 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide*HCl / CH₂Cl₂ / 72 h / 20 °C

4: 98 percent / aq. NaOH / methanol / 2 h / 20 °C

With 4-methyl-morpholine; sodium hydroxide; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; methanol; ethanol; dichloromethane; water;
DOI:10.3987/COM-01-9338

Reference yield:

: 657-27-2,10098-89-2,26124-78-7
L-Lysine hydrochloride

: 398460-96-3
n-tert-butoxycarbonyl-ε-(3-benzyloxy-1,4-dihydro-2-methyl-4-oxo-1-pyridyl)-L-norleucyl-β-alanine

Guidance literature:: Multi-step reaction with 4 steps

1: aq. NaOH / ethanol / 96 h / 20 °C

2: 37 percent / dioxane; H₂O / 56 h / 0 - 20 °C

3: 85 percent / N-methylmorpholine; 1-hydroxybenzotriazole; 1-[3-(dimethylamino)propyl]-3-ethylcarbodiimide*HCl / CH₂Cl₂ / 72 h / 20 °C

4: 98 percent / aq. NaOH / methanol / 2 h / 20 °C

With 4-methyl-morpholine; sodium hydroxide; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In 1,4-dioxane; methanol; ethanol; dichloromethane; water;
DOI:10.3987/COM-01-9338