2-CARBOXY-3-ETHYL NITROBENZOATE

Base Information

• Chemical Name: 2-CARBOXY-3-ETHYL NITROBENZOATE
• CAS No.: 16533-45-2
• Molecular Formula: C10H9 N O6
• Molecular Weight: 239.185
• Hs Code.: 2918990090
• Mol file: 16533-45-2.mol

Synonyms:2-CARBOXY-3-ETHYL NITROBENZOATE;2-(Ethoxycarbonyl)-6-nitrobenzoic acid;2-Carboxy-3-nitrobenzoic acid ethyl ester

Chemical Property of 2-CARBOXY-3-ETHYL NITROBENZOATE

Chemical Property:

• Melting Point: 157 oC**
• Boiling Point: 415.5±35.0 °C(Predicted)
• PKA: 1.90±0.30(Predicted)
• PSA: 109.42000
• Density: 1.421±0.06 g/cm3 (20 oC 760 Torr), Calc.*
• LogP: 1.99290
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

>98% ^*data from raw suppliers

2-(Ethoxycarbonyl)-6-nitrobenzoicacid >95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-CARBOXY-3-ETHYL NITROBENZOATE

There total 4 articles about 2-CARBOXY-3-ETHYL NITROBENZOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

3-nitrophthalic acid (603-11-2) → ethyl 2-carboxy-3-nitrobenzoate (16533-45-2)

Guidance literature:

With potassium carbonate; In ethanol; sulfuric acid;

Reference yield:

benzene-1,2-dicarboxylic acid (88-99-3,73607-73-5) → ethyl 2-carboxy-3-nitrobenzoate (16533-45-2)

Guidance literature:

Multi-step reaction with 2 steps

1: HNO₃+H₂SO₄

2: hydrogen chloride

With hydrogenchloride; sulfuric acid; nitric acid;

Reference yield:

ethanol (64-17-5) + 3-nitrophthalic acid (603-11-2) → ethyl 2-carboxy-3-nitrobenzoate (16533-45-2)

Guidance literature:

With hydrogenchloride;

upstream raw materials:

ethanol

3-nitrophthalic acid

benzene-1,2-dicarboxylic acid

Downstream raw materials:

ethyl 1-[(2'-cyano-[1,1']-biphenyl-4-yl)methyl]-2-ethoxy-1H-benzo[d]imidazole-7-carboxylate

ethyl 3-amino-2-<<(2'-cyanobiphenyl-4-yl)methyl>amino>benzoate

ethyl 2-[(2'-cyanobiphenyl-4-yl)methyl]amino-3-nitrobenzoate

2,3-diaminobenzoic acid

Refernces

• 1、 -. "Benzimidazole derivatives and their use". . . Retrieved 2008/06/13.