Technology Process of C32H43ClN2O11
There total 11 articles about C32H43ClN2O11 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 6 steps
1: triethylsilane; boron trifluoride diethyl etherate / dichloromethane / 2 h / 0 °C
2: N-ethyl-N,N-diisopropylamine; tetra-(n-butyl)ammonium iodide / dichloromethane / 24 h / 20 °C
3: tetrabutyl ammonium fluoride / tetrahydrofuran / 4 h / 0 - 20 °C
4: triethylamine / toluene; ethyl acetate / 2 h / 0 °C
5: lithium bromide / acetone / 1 h / 0 - 20 °C
6: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / N,N-dimethyl-formamide / 4 h / 80 °C / Inert atmosphere
With
triethylsilane; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; boron trifluoride diethyl etherate; tetrabutyl ammonium fluoride; tetra-(n-butyl)ammonium iodide; sodium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; lithium bromide;
In
tetrahydrofuran; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; acetone; toluene;
6: |Suzuki Coupling;
DOI:10.1016/j.bmc.2014.04.036
- Guidance literature:
-
Multi-step reaction with 2 steps
1: lithium bromide / acetone / 1 h / 0 - 20 °C
2: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / N,N-dimethyl-formamide / 4 h / 80 °C / Inert atmosphere
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate; lithium bromide;
In
N,N-dimethyl-formamide; acetone;
2: |Suzuki Coupling;
DOI:10.1016/j.bmc.2014.04.036
- Guidance literature:
-
Multi-step reaction with 6 steps
1: sodium acetate / methanol / 0 - 20 °C
2: sodium hydride / N,N-dimethyl-formamide / 0 °C
3: sulfuric acid / tetrahydrofuran / 0 - 20 °C
4: sodium hydride / N,N-dimethyl-formamide / 0 - 20 °C
5: potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride / dimethyl sulfoxide / 14 h / 80 °C / Inert atmosphere
6: (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sodium carbonate / N,N-dimethyl-formamide / 4 h / 80 °C / Inert atmosphere
With
(1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; sulfuric acid; potassium acetate; sodium acetate; sodium hydride; sodium carbonate;
In
tetrahydrofuran; methanol; dimethyl sulfoxide; N,N-dimethyl-formamide;
6: |Suzuki Coupling;
DOI:10.1016/j.bmc.2014.04.036