(3R,4S,5R,6R,7R)-3-hydroxy-5,6-isopropylidenedioxy-7-(4-methoxybenzyloxy)-2,4,6-trimethylnon-1-ene

Base Information

Chemical Name:(3R,4S,5R,6R,7R)-3-hydroxy-5,6-isopropylidenedioxy-7-(4-methoxybenzyloxy)-2,4,6-trimethylnon-1-ene
CAS No.:98049-35-5
Molecular Formula:C₂₃H₃₆O₅
Molecular Weight:392.536
Hs Code.:

Synonyms:(3R,4S,5R,6R,7R)-3-hydroxy-5,6-isopropylidenedioxy-7-(4-methoxybenzyloxy)-2,4,6-trimethylnon-1-ene

Suppliers and Price of (3R,4S,5R,6R,7R)-3-hydroxy-5,6-isopropylidenedioxy-7-(4-methoxybenzyloxy)-2,4,6-trimethylnon-1-ene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3R,4S,5R,6R,7R)-3-hydroxy-5,6-isopropylidenedioxy-7-(4-methoxybenzyloxy)-2,4,6-trimethylnon-1-ene

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3R,4S,5R,6R,7R)-3-hydroxy-5,6-isopropylidenedioxy-7-(4-methoxybenzyloxy)-2,4,6-trimethylnon-1-ene

There total 28 articles about (3R,4S,5R,6R,7R)-3-hydroxy-5,6-isopropylidenedioxy-7-(4-methoxybenzyloxy)-2,4,6-trimethylnon-1-ene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 98004-19-4
(2S,3R,4S,5R,6R,7R)-2,3-epoxy-1-iodo-5,6-isopropylidene-dioxy-7-(4-methoxybenzyloxy)-2,4,6-trimethylnonane

: 98049-35-5
(3R,4S,5R,6R,7R)-3-hydroxy-5,6-isopropylidenedioxy-7-(4-methoxybenzyloxy)-2,4,6-trimethylnon-1-ene

Guidance literature:: With copper; zinc; In ethanol; for 0.333333h; Heating;

Reference yield:

: 64638-70-6
3-O-benzyl-5,6-dideoxy-1,2-O-isopropylidene-3-C-methyl-α-D-ribo-hexofuranose

: 98049-35-5
(3R,4S,5R,6R,7R)-3-hydroxy-5,6-isopropylidenedioxy-7-(4-methoxybenzyloxy)-2,4,6-trimethylnon-1-ene

Guidance literature:: Multi-step reaction with 18 steps

1: trifluoroacetic acid / tetrahydrofuran; H₂O / 40 h / Ambient temperature

2: Pb(OAc)4 / benzene / 0.25 h / Ambient temperature

3: 88.9 percent / 1,2-dichloro-ethane / 17 h / Heating

4: 90.4 percent / LiAlH₄ / diethyl ether / 2 h / 0 °C

5: 76.2 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 2.5 h / -5 °C

6: 86.6 percent / H₂, NaHCO₃ / 10 percent Pd-C / ethanol / 5 h / Ambient temperature

7: 69.3 percent / DDQ / CH₂Cl₂ / 0.42 h / 16 °C

8: 72 percent / AlH₃ / diethyl ether / 1 h / Ambient temperature

9: 95 percent / pyridine / CH₂Cl₂ / 1 h / Ambient temperature

10: 94 percent / TsOH / acetone / 30 h / Ambient temperature

11: 100 percent / 1M KOH / methanol / 1 h / Ambient temperature

12: 91 percent / pyridinium chlorochromate, molecular sieves 3 Angstroem / CH₂Cl₂ / 0.25 h / Ambient temperature

13: 1,2-dichloro-ethane / 12 h / Heating

14: 99.7 percent / LiAlH₄ / tetrahydrofuran / 0.5 h / 0 °C

15: 97.7 percent / m-CPBA / CH₂Cl₂ / 2.5 h / -15 - -10 °C

16: 92 percent / Et₃N / benzene / 0.03 h / Ambient temperature

17: 97.6 percent / NaI / methanol / 1 h / Heating

18: 96 percent / Zn-Cu couple / ethanol / 0.33 h / Heating

With pyridine; aluminium hydride; lead(IV) acetate; potassium hydroxide; lithium aluminium tetrahydride; 3 A molecular sieve; hydrogen; copper; sodium hydrogencarbonate; toluene-4-sulfonic acid; triethylamine; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate; trifluoroacetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium iodide; zinc; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; water; 1,2-dichloro-ethane; acetone; benzene;

Reference yield:

: 64638-73-9
4,5-didesoxy-2-C-methyl-2-O-benzyl-3-O-formyl-D-erythro-al-pentose

: 98049-35-5
(3R,4S,5R,6R,7R)-3-hydroxy-5,6-isopropylidenedioxy-7-(4-methoxybenzyloxy)-2,4,6-trimethylnon-1-ene

Guidance literature:: Multi-step reaction with 16 steps

1: 88.9 percent / 1,2-dichloro-ethane / 17 h / Heating

2: 90.4 percent / LiAlH₄ / diethyl ether / 2 h / 0 °C

3: 76.2 percent / m-chloroperbenzoic acid / CH₂Cl₂ / 2.5 h / -5 °C

4: 86.6 percent / H₂, NaHCO₃ / 10 percent Pd-C / ethanol / 5 h / Ambient temperature

5: 69.3 percent / DDQ / CH₂Cl₂ / 0.42 h / 16 °C

6: 72 percent / AlH₃ / diethyl ether / 1 h / Ambient temperature

7: 95 percent / pyridine / CH₂Cl₂ / 1 h / Ambient temperature

8: 94 percent / TsOH / acetone / 30 h / Ambient temperature

9: 100 percent / 1M KOH / methanol / 1 h / Ambient temperature

10: 91 percent / pyridinium chlorochromate, molecular sieves 3 Angstroem / CH₂Cl₂ / 0.25 h / Ambient temperature

11: 1,2-dichloro-ethane / 12 h / Heating

12: 99.7 percent / LiAlH₄ / tetrahydrofuran / 0.5 h / 0 °C

13: 97.7 percent / m-CPBA / CH₂Cl₂ / 2.5 h / -15 - -10 °C

14: 92 percent / Et₃N / benzene / 0.03 h / Ambient temperature

15: 97.6 percent / NaI / methanol / 1 h / Heating

16: 96 percent / Zn-Cu couple / ethanol / 0.33 h / Heating

With pyridine; aluminium hydride; potassium hydroxide; lithium aluminium tetrahydride; 3 A molecular sieve; hydrogen; copper; sodium hydrogencarbonate; toluene-4-sulfonic acid; triethylamine; 3-chloro-benzenecarboperoxoic acid; pyridinium chlorochromate; 2,3-dicyano-5,6-dichloro-p-benzoquinone; sodium iodide; zinc; palladium on activated charcoal; In tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; 1,2-dichloro-ethane; acetone; benzene;