1,1'-(4-Methyl-1,3-phenylene)bis(3-ethylurea)

Base Information

Chemical Name:1,1'-(4-Methyl-1,3-phenylene)bis(3-ethylurea)
CAS No.:25635-03-4
Molecular Formula:C₁₃H₂₀N₄O₂
Molecular Weight:264.327
Hs Code.:
European Community (EC) Number:667-359-9

Synonyms:1,1'-(4-Methyl-1,3-phenylene)bis(3-ethylurea);AKOS017100482

Suppliers and Price of 1,1'-(4-Methyl-1,3-phenylene)bis(3-ethylurea)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
1,1'-(4-METHYL-1,3-PHENYLENE)BIS(3-ETHYLUREA) Aldrich
250mg
$ 57.00

Total 1 raw suppliers

Chemical Property of 1,1'-(4-Methyl-1,3-phenylene)bis(3-ethylurea)

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:4
Exact Mass:264.15862589
Heavy Atom Count:19
Complexity:309

Purity/Quality:

99%, ^*data from raw suppliers

1,1'-(4-METHYL-1,3-PHENYLENE)BIS(3-ETHYLUREA) Aldrich ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCNC(=O)NC1=CC(=C(C=C1)C)NC(=O)NCC

Technology Process of 1,1'-(4-Methyl-1,3-phenylene)bis(3-ethylurea)

There total 5 articles about 1,1'-(4-Methyl-1,3-phenylene)bis(3-ethylurea) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 75-04-7,85404-22-4
ethylamine

: 584-84-9,6144-18-9,26006-20-2
2,4-Toluene diisocyanate

: 25635-03-4
1,1'-(4-methyl-1,3-phenylene)bis(3-ethylurea)

Guidance literature:: In tetrahydrofuran; dichloromethane; for 24h; Inert atmosphere;
DOI:10.1021/ja105717u

Reference yield:

: 6935-99-5
2,4-bis(methoxycarbonylamino)toluene

: 25635-03-4
1,1'-(4-methyl-1,3-phenylene)bis(3-ethylurea)

Guidance literature:: Multi-step reaction with 2 steps

1: montmorillonite K₁₀ Clay / 1-methyl-pyrrolidin-2-one / 0.5 h / 190 °C / Microwave irradiation

2: 0 - 20 °C

With montmorillonite K₁₀ Clay; In 1-methyl-pyrrolidin-2-one;
DOI:10.1080/00397911.2020.1762093

Reference yield:

: 7450-62-6
2,4-bis-(ethoxycarbonylamino)toluene

: 25635-03-4
1,1'-(4-methyl-1,3-phenylene)bis(3-ethylurea)

Guidance literature:: Multi-step reaction with 3 steps

1: phosphorus pentoxide

2: ammonia

3: 110 °C

With phosphorus pentaoxide; ammonia;