2-(1H-Pyrazol-1-Yl)Acetic Acid

Base Information

Chemical Name:2-(1H-Pyrazol-1-Yl)Acetic Acid
CAS No.:16034-48-3
Molecular Formula:C5H6 N2 O2
Molecular Weight:126.115
Hs Code.:2933199090
European Community (EC) Number:801-091-7
DSSTox Substance ID:DTXSID60395444
Nikkaji Number:J3.160.020K
Wikidata:Q72503583
Mol file:16034-48-3.mol

Synonyms:2-(1H-Pyrazol-1-Yl)Acetic Acid;16034-48-3;1H-pyrazol-1-ylacetic acid;1-Pyrazoleacetic Acid;1H-Pyrazole-1-acetic acid;Pyrazol-1-yl-acetic acid;2-pyrazol-1-ylacetic acid;pyrazol-1-ylacetic acid;MFCD00228774;1H-Pyrazol-1-yl acetic acid;1-PyrazoleaceticAcid;2-(1-pyrazolyl)-acetic acid;SCHEMBL1073206;DTXSID60395444;LOSKNFQZTWYZHI-UHFFFAOYSA-N;HMS1759M05;2-(1H-Pyrazol-1-yl) acetic acid;BBL008568;CL3510;STK346008;AKOS000263940;CS-W002537;1H-Pyrazol-1-ylacetic acid, AldrichCPR;BS-13019;SY022023;AM20080433;BB 0258606;FT-0677878;EN300-23942;A883220;J-505359;F2124-0632;Z166653130

Suppliers and Price of 2-(1H-Pyrazol-1-Yl)Acetic Acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(1H-Pyrazol-1-yl)aceticAcid
100mg
$ 75.00

Matrix Scientific
Pyrazol-1-yl-acetic acid
1g
$ 24.00

Matrix Scientific
Pyrazol-1-yl-acetic acid
500mg
$ 10.00

Crysdot
2-(1H-Pyrazol-1-yl)aceticacid 97%
25g
$ 341.00

Chemenu
1H-pyrazol-1-ylaceticacid 95+%
10g
$ 195.00

Chemenu
1H-pyrazol-1-ylaceticacid 95+%
5g
$ 126.00

Chemenu
1H-pyrazol-1-ylaceticacid 95+%
25g
$ 538.00

ChemBridge Corporation
1H-pyrazol-1-ylaceticacid 95%
10 g
$ 224.00

American Custom Chemicals Corporation
1H-PYRAZOL-1-YLACETIC ACID 95.00%
5G
$ 1295.03

American Custom Chemicals Corporation
1H-PYRAZOL-1-YLACETIC ACID 95.00%
2.5G
$ 1065.66

Total 28 raw suppliers

Chemical Property of 2-(1H-Pyrazol-1-Yl)Acetic Acid

Chemical Property:

Vapor Pressure:0.000477mmHg at 25°C
Melting Point:171-172 °C
Refractive Index:1.588
Boiling Point:301.1°Cat760mmHg
PKA:3.58±0.10(Predicted)
Flash Point:135.9°C
PSA：55.12000
Density:1.33g/cm³
LogP:-0.03230
Storage Temp.:2-8°C
XLogP3:-0.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:126.042927438
Heavy Atom Count:9
Complexity:116

Purity/Quality:

97% ^*data from raw suppliers

2-(1H-Pyrazol-1-yl)aceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CN(N=C1)CC(=O)O
General Description 2-(1H-Pyrazol-1-yl)acetic acid (also known as pyrazole-1-acetic acid) serves as a key precursor in the synthesis of heterocyclic β-diketones, as demonstrated by its reaction with sodium acetophenone to form 1-phenyl-4-(pyrazole-1-yl)butane-1,3-dione. This β-diketone ligand exhibits keto-enol tautomerism and coordinates with transition metal ions (Mn(II), Fe(II), Co(II)) in its enolic form, forming distorted octahedral complexes. The resulting metal complexes show enhanced antimicrobial and antifungal activities compared to the free ligand, highlighting the potential of 2-(1H-Pyrazol-1-yl)acetic acid-derived compounds in biocidal applications.

Technology Process of 2-(1H-Pyrazol-1-Yl)Acetic Acid

There total 8 articles about 2-(1H-Pyrazol-1-Yl)Acetic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 10199-61-8
pyrazol-1-yl acetic acid ethyl ester

: 16034-48-3
pyrazol-1-yl-acetic acid

Guidance literature:: pyrazol-1-yl acetic acid ethyl ester; With water; sodium hydroxide; at 20 - 30 ℃; for 3h;

With hydrogenchloride; In water;
DOI:10.1134/S1070363214080350