1-(4-fluorophenyl)-3-(4-trifluoromethylphenyl)-propen-3-one

Base Information

• Chemical Name: 1-(4-fluorophenyl)-3-(4-trifluoromethylphenyl)-propen-3-one
• CAS No.: 256424-38-1
• Molecular Formula: C₁₆H₁₀F₄O
• Molecular Weight: 294.248
• Mol file: 256424-38-1.mol

Synonyms:1-(4-fluorophenyl)-3-(4-trifluoromethylphenyl)-propen-3-one

Chemical Property of 1-(4-fluorophenyl)-3-(4-trifluoromethylphenyl)-propen-3-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-fluorophenyl)-3-(4-trifluoromethylphenyl)-propen-3-one

There total 2 articles about 1-(4-fluorophenyl)-3-(4-trifluoromethylphenyl)-propen-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1-(4-trifluoromethylphenyl)ethanone (709-63-7) + 4-fluorobenzaldehyde (459-57-4) → 1-(4-fluorophenyl)-3-(4-trifluoromethylphenyl)-propen-3-one (256424-38-1)

Guidance literature:

With acid;

DOI:10.1002/(SICI)1521-3773(19991115)38:22<3373::AID-ANIE3373>3.0.CO;2-F

Reference yield:

→ chloroform-d1 (865-49-6) + 1-(4-fluorophenyl)-3-(4-trifluoromethylphenyl)-propen-3-one (256424-38-1)

Guidance literature:

Reference yield: 65.0%

2-(trimethylsilyloxy)-3-methyl-1-butene (17510-45-1) + spiro[3.5]non-7-en-6-one (221342-49-0) + 1-(4-fluorophenyl)-3-(4-trifluoromethylphenyl)-propen-3-one (256424-38-1) → C30H32F4O3 (221342-43-4)

Guidance literature:

2-(trimethylsilyloxy)-3-methyl-1-butene; spiro[3.5]non-7-en-6-one; With titanium(IV) isopropylate; titanium tetrachloride; In dichloromethane;

1-(4-fluorophenyl)-3-(4-trifluoromethylphenyl)-propen-3-one; In dichloromethane;

DOI:10.2533/000942904777678082

upstream raw materials:

1-(4-trifluoromethylphenyl)ethanone

4-fluorobenzaldehyde

Downstream raw materials:

C₃₀H₃₂F₄O₃

C₃₀H₂₆F₄O₂

C₃₀H₂₈F₄O₂

C₃₆H₄₃F₅OSi